DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8560 and CG7025

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	141/433 - (32%)
Similarity:	217/433 - (50%)	Gaps:	32/433 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LKLFAVVLLLASVALAVE---------NYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRS 57
            :.|.::.::||.|.||..         .||.|.:|.:......::.:|.:|:  |..:.|.|...
  Fly     1 MALNSLPIVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLA--EDRENFRLWHE 63

  Fly    58 LDASSRVMVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKA 122
            ......:|:.|......|..::|..|...:...|..|.:..|...|..      .|.:.:..:..
  Fly    64 AKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLK------ASRDGTFGWTK 122

  Fly   123 FHRHAEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWI 187
            ::..|||.|:||::.||||:.....:.|:|||.|.|:.|.|:......|   |.:::.|||||||
  Fly   123 YNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPG---VLIESNIHAREWI 184

  Fly   188 AHAGALYVIHQLVENFAANSELLKDF----DWVILPVVNPDGYEYSHTTTRMWRKTRKPIS-SAC 247
            ..|.|.::|::.:   .:..||::|.    ||.|:||:|.||:.|:|...|||||||:|.. |:|
  Fly   185 TSATATWLINEFL---TSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSC 246

  Fly   248 YGTDANRNFDFHWGE-VGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNY 311
            .|.|.|||:|.||.| .||||..|::.:.|...|||||.|.:.:.::|:..:....|..|||...
  Fly   247 IGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQL 311

  Fly   312 LLYPWGWT-SALPSSWRDNDEVAQGGADAIKSAT-GTKYTVGSSTNVLYAAAGGSDDYAFGVANF 374
            ||.|:|.| ...|.::.|..|||:...||::|.. ||.|..||:..:||.|:|.:.|:|:.....
  Fly   312 LLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGV 376

  Fly   375 PVSITMEL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKVAD 416
            .:|.|:|. ..|..||......|.....|..:||.|:.:|..|
  Fly   377 EISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	12/68 (18%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	114/299 (38%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	12/68 (18%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	114/298 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466994
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750