DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and AGBL3

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_848658.3	Gene:	AGBL3 / 340351	HGNCID:	27981	Length:	920	Species:	Homo sapiens

Alignment Length:	193	Identity:	44/193 - (22%)
Similarity:	69/193 - (35%)	Gaps:	79/193 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 IKTIT--ITNGDGKTGKNVVFLDAGIHARE----WIAHAGALYVIHQLVENFAANSELLKD-FDW 215
            |.|||  :.|.|.:..|.|: |.|.:|..|    ||......|::..     :::::||:| |.:
Human   339 ILTITTPLKNSDSRKRKAVI-LTARVHPGETNSSWIMKGFLDYILGN-----SSDAQLLRDTFVF 397

  Fly   216 VILPVVNPDG-----YEYSHTTTRMWRKTRKPISSACYGTDANRNF------------------- 256
            .::|::||||     |..|                 ..|.|.|||:
Human   398 KVVPMLNPDGVIVGNYRCS-----------------LAGRDLNRNYTSLLKESFPSVWYTRNMVH 445

  Fly   257 ------------DFHWGEVGAS------SYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKF 301
                        |.|    |.|      .|.|..:.:.:|.:.:   |.|..::||.....||
Human   446 RLMEKREVILYCDLH----GHSRKENIFMYGCDGSDRSKTLYLQ---QRIFPLMLSKNCPDKF 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	44/193 (23%)
AGBL3	NP_848658.3	M14_AGBL2-3_like	310..570	CDD:133117	44/193 (23%)
AGBL3	NP_848658.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	641..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900