DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and CG8945

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	125/449 - (27%)
Similarity:	210/449 - (46%)	Gaps:	60/449 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLP----RSLDASSRVMVKPEDQEGFEHLLEK 80
            :||.|:|:.:..::  |:|:.......:..|...|.    .||...:.|:|.|:....|:..|..
  Fly   980 SYDKYQIWRLKPQD--EEQVRALEEFKKGEDGVKLQWLKGPSLRGLTDVLVPPKMLVDFQGTLNY 1042

  Fly    81 YGVNYSVINENFGESLRQE---RDENQNQRLMNLR-SAERSVSFKAFHRHAEINAYLDELAAAYP 141
            .|:.:.|:..:.|:::..|   .|..|..|....| :|...:::..:|.|.||..||:.:...:|
  Fly  1043 EGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHNHDEIVKYLETVRMRHP 1107

  Fly   142 SRVSVQVAGKSYENRDI--------KTITITNGDG-----------KTGK-NVVFLDAGIHAREW 186
            ..|.:...|:|:|.|.:        :|....|.||           |:|: |.||::||.....|
  Fly  1108 QLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSGQANAVFVEAGAQGLAW 1172

  Fly   187 IAHAGALYVIHQLVENFAANS-----ELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKP---- 242
            |..|.|.::|.:|:.....|.     |.:::..|.|:||:|||||.|||...|.|:|:|..
  Fly  1173 IGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSHEYDRFWKKSRSQHQTP 1237

  Fly   243 -----ISSA-------------CYGTDANRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIR 289
                 :.||             |||.|.:||:.:|||:.|:|...|::.:.|...||||||:.:.
  Fly  1238 PPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCNEFYAGPAPFSEPETKAVS 1302

  Fly   290 DILLSLTGRGKFYLTLHSYGNYLLYPWGWTSALPSSWRDND-EVAQGGADAI-KSATGTKYTVGS 352
            :.|:....:.|.|::|.:||..:.||....|...|...|:. :||..|.|.: |..:.::|.|.:
  Fly  1303 EFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMVGTDGLRKKGSKSRYKVDA 1367

  Fly   353 STNVLYAAAGGSDDYAFGVANFPVSITMELPAGGT-GFNPSTSQIEGFVSETWVGIKAM 410
            |.:::...:|.:|.:|......|.|.|::|...|. |:...:|.||....:.:..|..|
  Fly  1368 SNDLIEQRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIEPTARDAFEIISGM 1426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	14/72 (19%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	101/338 (30%)
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	14/71 (20%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	101/338 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920