DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and CG3108

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	137/376 - (36%)
Similarity:	208/376 - (55%)	Gaps:	17/376 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VENYDGYKIYDINARNAFEKQLLLRLSGNEAYD---FFDLPRSLDASSRVMVKPEDQEGFEHLLE 79
            :..|||.:::.|..:...:|::...|...  ||   :.::.:.:|    .::||:.....|..:.
  Fly   720 LRRYDGAQVWRIVVQTDKDKRMADELQSK--YDGQLWKEVKQEVD----YLLKPQVLAAAERHIR 778

  Fly    80 KYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRHAEINAYLDELAAAYPSRV 144
            ...::..|:.:|....:.:|....:....:..|...| ::::|:||..:|:.::|.:|..||...
  Fly   779 AANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHR-LTWQAYHRLEDIHGFIDYMAKTYPDIC 842

  Fly   145 SVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAGALYVIHQLVENFAANSEL 209
            |.::.|.|.|.|.:|.:.|:||:.:...  :::|.|:||||||:.|...|:.:||||.:....|.
  Fly   843 STEIIGYSVEKRPLKILKISNGNARNPG--IWIDGGMHAREWISPATVTYIANQLVEGWEDLPEH 905

  Fly   210 LKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISSACYGTDANRNFDFHWGEVGASSYSCSDTF 274
            ::..:|.|.||.|||||||||||.|:|||..:.....|.|.|.||||.:.||..|.|:..||.|:
  Fly   906 MRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTY 970

  Fly   275 KGETAFSEPETQLIRDILLSLTGRGKF--YLTLHSYGNYLLYPWGWTSALPSSWRDNDEVAQGGA 337
            :|..|||||||..|...:.... |..|  ||:.||||.|:|||||:...|.....|.|.||:...
  Fly   971 RGSKAFSEPETFYISKFISGFP-RETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQAG 1034

  Fly   338 DAIKSATGTKYTVGSSTNVLYAAAGGSDDYAFGVANFPVSITMELPAGGTG 388
            .:|..:||.|||||||...||.|||||||:|.|:|....:.|:|:  |.||
  Fly  1035 TSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEM--GDTG 1083

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	11/71 (15%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	119/268 (44%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	11/72 (15%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	119/268 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466931
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750