DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	322	Identity:	100/322 - (31%)
Similarity:	156/322 - (48%)	Gaps:	47/322 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 YLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTG-----KNVVFLDAGIHAREWIAHAG 191
            |:..:|...||.|.::..|::.|.|.:..:.|    ||..     |..|:||.|.|||||.|...
Worm    44 YIKGVAHDNPSFVQLKTIGRTREGRPLLGVRI----GKPALPGKRKIAVWLDGGNHAREWPAFHV 104

  Fly   192 ALYVIHQLVENFAANSELLK---DFDWVILPVVNPDGYEYSHTTT----RMWRKTRKP------- 242
            |:|.|.:||..:.::.::.|   ..|..:.||:||||:.||.|:|    |.|||.|.|
Worm   105 AVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRAMIRQWRKNRAPENCTGTG 169

  Fly   243 ---ISSACYGTDANRNFDFHWGEVGAS------SYSCSDTFKGETAFSEPETQLIRDILLSLTGR 298
               ....|.|.|.|||:|     :|.|      :..|||.|:|...||||||:.:||.::|....
Worm   170 PFQTDICCEGVDLNRNYD-----IGFSHKNYPFNNPCSDEFQGPRPFSEPETRAVRDFIMSSEIY 229

  Fly   299 GKFY--LTLHSYGNYLLYPWGWTS-ALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAA 360
            |:.|  :::|::|...:.|:.:.. ..|...:|.:.:|...||.:.:...|||.||::.::|..|
Worm   230 GRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLEILANRAADRVFAYRETKYRVGTAADMLGTA 294

  Fly   361 AGGSDDYAFGVANFPVS--ITMELPAG---GTGFNPSTSQIEGFVSETWVGIKAMAQKVADK 417
            .||:.|:.  ..|.|..  ..:|||..   ...|......:.....|||:||:.:..:|.::
Worm   295 TGGATDWI--KKNTPTKYVYVLELPPDMKTWFAFQVKPHWLIPIGKETWLGIEVIFDQVVEE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	99/317 (31%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	94/303 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830