Protein Alignment CG8560 and CPB1

DIOPT Version :10

• Sequence 1: NP_648120.3
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001862.2
• Gene: CPB1 / 1360
• HGNCID: 2299
• Length: 417
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 140/427 - (32%)
• Similarity: 218/427 - (51%)
• Gaps: 34/427 - (7%)

  Fly     8 VLLLASVALAV-----ENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFF--DLPRSLDASSRV- 64
            :|:|.:||||.     |:::|.|::.:|..:.....::..|:.....||:  |....:...|.|
Human     4 LLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVD 68

  Fly    65 -MVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRHAE 128
             .||.||....|::|::..:.|.|:..|....:..:.|.         |......|::.:::...
Human    69 FRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDS---------RVRATGHSYEKYNKWET 124

  Fly   129 INAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKN--VVFLDAGIHAREWIAHAG 191
            |.|:..::|...|:.:|..|.|.::|.|.|..:.:    ||.|:|  .:|:|.|.||||||:.|.
Human   125 IEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV----GKAGQNKPAIFMDCGFHAREWISPAF 185

  Fly   192 ALYVIHQLVENFAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKP-ISSACYGTDA 252
            ..:.:.:.|..:...   :|||...|:.:|||:|.|||.|:.|.:|.|||||.. ..|:|.|||.
Human   186 CQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDP 250

  Fly   253 NRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWG 317
            |||||..|.|:|||...|.:|:.|..|.||.||:.:.|.:.:.....|.|||:|||...::||:.
Human   251 NRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS 315

  Fly   318 WTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAF--GVANFPVSITM 380
            :...|..:..:.:.:|:.....:.|..|||||.|.....:|.|||||||:|:  |:.   .|.|.
Human   316 YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIR---YSFTF 377

  Fly   381 EL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKVAD 416
            || ..|..||....|||.....||::.||.:|..|.:
Human   378 ELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_648120.3	Propep_M14	27..99	CDD:460505	16/75 (21%)
		M14_CP_A-B_like	123..414	CDD:349433	111/299 (37%)
CPB1	NP_001862.2	Propep_M14	28..104	CDD:460505	16/75 (21%)
		M14_CPB	114..413	CDD:349443	112/305 (37%)