Protein Alignment CG8560 and CPA3

DIOPT Version :10

• Sequence 1: NP_648120.3
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 115/425 - (27%)
• Similarity: 215/425 - (50%)
• Gaps: 24/425 - (5%)

  Fly     1 MLKLFAVVLLLASVALAVENYDGYKIYDINARNAFEKQLLLRLSGNEAYDFFDLPRSLDASSRVM 65
            |..:..|.|:..::|:|...:|..|::.:..::..:..::..|:.....||:....:...::.:|
Human     1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMM 65

  Fly    66 ----VKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRH 126
                |..::.:..:..|::..::|.::..:..|.:.::.|..::        .....|:..::..
Human    66 VDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKED--------IPGRHSYAKYNNW 122

  Fly   127 AEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAG 191
            .:|.|:.:::...||..||....|.:.|:..:..:.|  |:....:..:|.|.|||||||::.|.
Human   123 EKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI--GEKNERRKAIFTDCGIHAREWVSPAF 185

  Fly   192 ALYVIHQLVENFAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTR-KPISSACYGTDA 252
            ..:.::|..:.:..|   ::||...::.||||.|.|||.:|.|..|||||.| |..:|.|.|||.
Human   186 CQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDL 250

  Fly   253 NRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWG 317
            ||||:..|..:..::..|:|.::|....||.||:.:.:.:.|.....|.|:|.|||...||:|:|
Human   251 NRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYG 315

  Fly   318 WTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAF--GVANFPVSITM 380
            :||.||.:..|..:||:.|.|.:.:...|:|..|...:.:|..:|.|.|:|:  |:.:   :...
Human   316 YTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKH---TFAF 377

  Fly   381 EL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKV 414
            || ..|..||....|:|:....||.:.:|.:|:.:
Human   378 ELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYI 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_648120.3	Propep_M14	27..99	CDD:460505	8/75 (11%)
		M14_CP_A-B_like	123..414	CDD:349433	98/297 (33%)
CPA3	NP_001861.2	Propep_M14	27..103	CDD:460505	8/75 (11%)
		M14_CPB	114..413	CDD:349443	99/304 (33%)