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Protein Alignment CG8560 and CPA2

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	428	Identity:	158/428 - (36%)
Similarity:	232/428 - (54%)	Gaps:	30/428 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AVVLLLASVAL-----AVENYDGYKIYDINARNAFEKQLLLRLSGNE--AYDFFDLPRSLDASSR 63
            |:.|:|...||     .:|.:.|.::.:|...|..:.:.||:|...|  ..||:..|.:...::.
Human     2 AMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAH 66

  Fly    64 VMVKPEDQEGFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERS--VSFKAFHRH 126
            |.|...:.:..:..||..|:.||::.|:....|.:|.:|    .|.| |..|||  .:|.|:|..
Human    67 VRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEE----MLFN-RRRERSGNFNFGAYHTL 126

  Fly   127 AEINAYLDELAAAYPSRVSVQVAGKSYENRDIKTITI-TNGDGKTGKNVVFLDAGIHAREWIAHA 190
            .||:..:|.|.|.:|..||....|.|:|||.:..:.. |.||    |..::||||||||||:..|
Human   127 EEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD----KPAIWLDAGIHAREWVTQA 187

  Fly   191 GALYVIHQLVENFAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPIS-SACYGTD 251
            .||:..:::|.::..:   :.:|...|..:|||.|||||.:|.|..|||||||..:| |.|.|.|
Human   188 TALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVD 252

  Fly   252 ANRNFDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPW 316
            .|||:|..:|..||||..|||::.|.:|.||.|.:.|.|.:.| .|:.|.::|||||...|::|:
Human   253 PNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS-HGKVKAFITLHSYSQLLMFPY 316

  Fly   317 GWTSALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDD--YAFGVANFPVSIT 379
            |:.......:.:..||||..|.:::|..||||.||...:|:|.|:|||.|  |.:|:   ..|..
Human   317 GYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI---KYSFA 378

  Fly   380 MEL-PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKVAD 416
            .|| ..|..||.....||.....|||:|:||:.:.|.|
Human   379 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 416

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.