DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8560 and cpo.1

DIOPT Version :9

Sequence 1:	NP_001261516.1	Gene:	CG8560 / 38830	FlyBaseID:	FBgn0035781	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_031748368.1	Gene:	cpo.1 / 100145253	XenbaseID:	XB-GENE-989447	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	361	Identity:	119/361 - (32%)
Similarity:	186/361 - (51%)	Gaps:	33/361 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 FEHLLEKYGVNYSVI---------NENFGESLRQERDENQNQRLMNLRSAERSVSFKAFHRHAEI 129
            |:..|.:|.:.:.|:         :.|.|:..||::             ......:..:|...||
Frog    82 FKENLHQYSIPFEVMIKDVQKLIDSSNVGDYRRQKK-------------ILAEFDYTTYHPMDEI 133

  Fly   130 NAYLDELAAAYPSRVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAGALY 194
            ..::|::..||...||:...|.:||.|.|....|.....|. |.::::|.|||||||||.|...:
Frog   134 YQWMDQVKEAYSDLVSMHYLGSTYELRPIYYFKIGWPSDKQ-KKIIWMDCGIHAREWIAVAYCQW 197

  Fly   195 VIHQLVENFAAN---SELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTRKPISS-ACYGTDANRN 255
            .:.:::|....|   .::|.:.|:.|:||:|.||:.||....|:|||:|.|.:: :|||.|.|||
Frog   198 FVKEILETHKTNPLLQKVLHNIDFYIVPVLNIDGFVYSWNVNRLWRKSRSPHNNGSCYGVDLNRN 262

  Fly   256 FDFHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWGWTS 320
            |:..||.:|||:....:|:.|....||||...:..:|.||......:||:||||..||.|:|:|.
Frog   263 FNSKWGSIGASNNCRDETYCGTGPASEPEVNAVSKLLGSLKSDVLCFLTIHSYGQLLLLPYGYTK 327

  Fly   321 ALPSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYA--FGVANFPVSITMEL- 382
            ....:..:...|||..|..::...||:|.|||::::||:.:|.|.|:|  .|: ||  |.|.||
Frog   328 DPSINHEEMINVAQKAAAKLQEKHGTEYRVGSTSHLLYSNSGSSRDWATDLGI-NF--SYTFELR 389

  Fly   383 PAGGTGFNPSTSQIEGFVSETWVGIKAMAQKVADKY 418
            ..|..||....:||.....||..|:..:.:.|..|:
Frog   390 DTGAHGFILPANQIRPTCEETMAGVMTIVEHVDAKF 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8560	NP_001261516.1	Propep_M14	29..98	CDD:280416	6/32 (19%)
CG8560	NP_001261516.1	M14_CP_A-B_like	123..414	CDD:199844	109/297 (37%)
cpo.1	XP_031748368.1	Propep_M14	36..105	CDD:396700	4/22 (18%)
cpo.1	XP_031748368.1	M14_CPO	124..421	CDD:349466	109/300 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920