back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18417 and CPA5

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001120913.1	Gene:	CPA5 / 93979	HGNCID:	15722	Length:	436	Species:	Homo sapiens

Alignment Length:	415	Identity:	113/415 - (27%)
Similarity:	195/415 - (46%)	Gaps:	55/415 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 EALSELVKNASYYEVFSELNAGNPGKI--------------MVHPHEQVNFVQ-LMEENNVKYDI 93
            :.|..|.|:.....:..:|....|.|:              |..|..::..:: .:|.:.:.|.|
Human    41 QVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSI 105

  Fly    94 INRNVGLTL---------SRQFE--TNRMLRHWFPYNGRLGTERYYNHEEINQFIEDLAGEHPRR 147
            :.:::.:.|         ||:.|  ||.     |.|:.      |:..|||..:|::...||...
Human   106 MIKDIQVLLDEERQAMAKSRRLERSTNS-----FSYSS------YHTLEEIYSWIDNFVMEHSDI 159

  Fly   148 VFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREWISPAAATYLINQLVYNLEDN-- 210
            |....:|.|:|.:.:..:..:.|.:|.  ..|.:|.|.|:||||:.|...:..|::|.:...:
Human   160 VSKIQIGNSFENQSILVLKFSTGGSRH--PAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRV 222

  Fly   211 -ADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTR--KPSSSDCIGTDPNRNFDFHWNEEGAS 272
             .|:|...|..|..|.||||:.:|.  ...|:|||.:  :|... |||.|.|||:...:...|::
Human   223 LTDILNAMDIFIELVTNPDGFAFTH--SMNRLWRKNKSIRPGIF-CIGVDLNRNWKSGFGGNGSN 284

  Fly   273 DDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWTAAVPDTEEDLHE 337
            .:||...|.|..|.||||...:.:.|.:: ...:..:::|||..:::||:|........:.:|::
Human   285 SNPCSETYHGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYD 348

  Fly   338 VAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGFPISFTMEL-PFGGTGFDPPASD 401
            :|.....|:.:..|..|..|..:||: |.|||.:.|:|:::|...:|:.|| ..|..||..||:.
Human   349 LAKDAVEALYKVHGIEYIFGSISTTL-YVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQ 412

  Fly   402 IDSIVKETWVGIAAMARKVIQKYPL 426
            |....:|||     ||.:.|.::.|
Human   413 IIPTAQETW-----MALRTIMEHTL 432

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.