Protein Alignment CG18417 and ECM14

DIOPT Version :10

• Sequence 1: NP_648119.1
• Gene: CG18417 / 38829
• FlyBaseID: FBgn0035780
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_012000.1
• Gene: ECM14 / 856533
• SGDID: S000001174
• Length: 430
• Species: Saccharomyces cerevisiae
• Alignment Length: 453
• Identity: 120/453 - (26%)
• Similarity: 204/453 - (45%)
• Gaps: 78/453 - (17%)

  Fly     1 MTVVW-----VILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFS 60
            |..:|     |:||::  ....|||  ..|..|.:|..:|:..|....:.::.|..:   |:|::
Yeast     4 MNSLWGCFLFVLLAVT--GAVQGLQ--EDYSEYAVYRFTSDNYSTLVRDVIAPLTDD---YDVWT 61

  Fly    61 ELNAGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTE 125
            ..|.....|:.....||:|..|::.:|                    .|.::::..|.:..:..|
Yeast    62 RSNNFIDIKLPKEIGEQINDGQVIIDN--------------------MNELIQNTLPTSQMMARE 106

  Fly   126 R-------------YYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRN-- 175
            :             |.:.:.|..:::.|....|..|.::.:||::|||.||.:.|:......|
Yeast   107 QAVFENDYDFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNPE 171

  Fly   176 KNVILVDGGFHAREWISPAAATYLINQLVY---NLEDNADLLLDFDWVILPVVNPDGYEYTQLSE 237
            |..|::.||.|||||||.:...:.:.||:.   :.:.....|.|.|::::||.|||||.|| .|.
Yeast   172 KKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYT-WSH 235

  Fly   238 DTRMWRKTRKPSS-SDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEAL--------V 293
            | |:|||.|:.:. ..|:|.|.:.:|.|.|  |.|....|...|:|..||...||.        .
Yeast   236 D-RLWRKNRQRTHVPQCLGIDIDHSFGFQW--EKAHTHACSEEYSGETPFEAWEASAWYKYINET 297

  Fly   294 VGDL-IHSYVDRGQMYLTLHSYGSLILYPWGWTA-AVPDTEEDLHEVAAAGQSAIQEATGTIYKI 356
            .||. |:.|:|       :|||...||||:.::. |:|...|:|.|::.....||:..:|..|.:
Yeast   298 KGDYKIYGYID-------MHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDV 355

  Fly   357 -----GPSATTINYAASGASDDYAFNAGFPISFTMEL-PFGGTGFDPPASDIDSIVKETWVGI 413
                 ...:.......:|::.|:.::.....:|.::| ..|..||..|..:|..:.|||:..:
Yeast   356 ISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPVGKETYAAL 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<70..105	CDD:460505	5/34 (15%)
		Peptidase_M14	133..412	CDD:459730	93/300 (31%)
ECM14	NP_012000.1	M14_CP_A-B_like	121..425	CDD:349433	94/309 (30%)