Protein Alignment CG18417 and AGBL2

DIOPT Version :9

• Sequence 1: NP_648119.1
• Gene: CG18417 / 38829
• FlyBaseID: FBgn0035780
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_079059.2
• Gene: AGBL2 / 79841
• HGNCID: 26296
• Length: 902
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 87/413 - (21%)
• Similarity: 143/413 - (34%)
• Gaps: 115/413 - (27%)

  Fly    22 TNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEV------FSELNAGNPGKIMVHPHEQVNF 80
            |||:..:..:.|.:..:...:...:..|:|..|.|.|      :|:|:|...           |.
Human   298 TNKHTQWFYFRVQNTRKDATYRFTIVNLLKPKSLYTVGMKPLLYSQLDANTR-----------NI 351

  Fly    81 VQLMEENNVKYDIINRNVG------LTLSRQFETNR---MLRHWFPYNGRLGTERYYNHEEINQF 136
            ....|.|.:||...|.:.|      ||.:.||..::   ...|::|          |.:.::..:
Human   352 GWRREGNEIKYYKNNTDDGQQPFYCLTWTIQFPYDQDTCFFAHFYP----------YTYTDLQCY 406

  Fly   137 IEDLAGEHPRRVF--LKTVGRSYEGRWLKTITITN-----GDARRNKNVIL---VDGGFHAREWI 191
            :..:|....:..|  |:|:.||..|..:..:||||     .:|...|.|:|   |..|.....|:
Human   407 LLSVANNPIQSQFCKLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVHPGESNGSWV 471

  Fly   192 SPAAATYLINQLVYNLEDNADLLLD-FDWVILPVVNPDG-----YEYTQLSEDTRMWRKTRKPSS 250
            ......::::.     ..:|.||.| |.:.:||::||||     |..:....|.....||....|
Human   472 MKGFLDFILSN-----SPDAQLLRDIFVFKVLPMLNPDGVIVGNYRCSLAGRDLNRHYKTILKES 531

  Fly   251 SDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYL------ 309
            ..||           |......          .:...|.|.|:..| .|.:..:..::|
Human   532 FPCI-----------WYTRNMI----------KRLLEEREVLLYCD-FHGHSRKNNIFLYGCNNN 574

  Fly   310 ----TLHSYGSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGA 370
                .||..    ::|.......|| :...|......|.. :|.||.:
Human   575 NRKYWLHER----VFPLMLCKNAPD-KFSFHSCNFKVQKC-KEGTGRV----------------- 616

  Fly   371 SDDYAFNAGFPISFTMELPFGGT 393
               ..:..|...|:|||..|||:
Human   617 ---VMWRMGILNSYTMESTFGGS 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	6/33 (18%)
		M14_CP_A-B_like	127..420	CDD:199844	62/293 (21%)
AGBL2	NP_079059.2	GVQW	105..>120	CDD:290611
		M14_AGBL2-3_like	407..666	CDD:133117	61/283 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	746..770
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	796..879

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900