DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18417 and CG8945

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_573190.1	Gene:	CG8945 / 32693	FlyBaseID:	FBgn0030815	Length:	1430	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	125/468 - (26%)
Similarity:	210/468 - (44%)	Gaps:	90/468 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPG---------------KI 70
            |...|:.|:|:.:..:.....  .||.|..|             |..|               .:
  Fly   977 RRISYDKYQIWRLKPQDEEQV--RALEEFKK-------------GEDGVKLQWLKGPSLRGLTDV 1026

  Fly    71 MVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGR------LGTERYYN 129
            :|.|...|:|...:....:.::::..:||..::.:......|:...|...|      :...||:|
  Fly  1027 LVPPKMLVDFQGTLNYEGIAHEVLIFDVGKAIAYELTKEDYLQTTRPSKPRPTAPPPMTWNRYHN 1091

  Fly   130 HEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWL--------KTITITNGDA--------RRNK-- 176
            |:||.:::|.:...||:.|.|..:|||:|||.|        :|....|.|.        |:.|
  Fly  1092 HDEIVKYLETVRMRHPQLVELIHIGRSFEGRPLIVVKIESKQTAAAANNDGLHTIKRPKRKRKSG 1156

  Fly   177 --NVILVDGGFHAREWISPAAATYLINQLVYNLEDN-----ADLLLDFDWVILPVVNPDGYEYTQ 234
              |.:.|:.|.....||.|||||::|.:|:..::.|     .:.:.:..|.|:||:|||||.|:.
  Fly  1157 QANAVFVEAGAQGLAWIGPAAATWMIAELLRLMKTNKSNEDVEFIRNTTWYIMPVLNPDGYAYSH 1221

  Fly   235 LSEDTRMWRKTRK------PS----------------SSDCIGTDPNRNFDFHWNEEGASDDPCD 277
              |..|.|:|:|.      ||                ...|.|.|.:||:.:||.:.|:|..||:
  Fly  1222 --EYDRFWKKSRSQHQTPPPSGLLDSAMTWLQQKRGPDKVCYGVDLDRNWLYHWGKRGSSKAPCN 1284

  Fly   278 NIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWTAAV-PDTEEDLHEVAAA 341
            ..|||..||||||...|.:.:..|..:.::|::|.:||.:|.||....:.. .:..:|..:||..
  Fly  1285 EFYAGPAPFSEPETKAVSEFLMDYRTQIKLYISLQAYGQVISYPVKANSTFNSERLDDFLDVAMV 1349

  Fly   342 GQSAI-QEATGTIYKIGPSATTINYAASGASDDY-AFNAGFPISFTMELPFGGT-GFDPPASDID 403
            |...: ::.:.:.||:..|...|. ..||.:|.: |:..|.|.|:|::|...|. |:..|:|.|:
  Fly  1350 GTDGLRKKGSKSRYKVDASNDLIE-QRSGCADAFAAYEIGIPFSYTLQLADNGVHGYLLPSSAIE 1413

  Fly   404 SIVKETWVGIAAM 416
            ...::.:..|:.|
  Fly  1414 PTARDAFEIISGM 1426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	6/48 (13%)
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	105/341 (31%)
CG8945	NP_573190.1	Propep_M14	988..1058	CDD:280416	12/84 (14%)
CG8945	NP_573190.1	M14_CP_A-B_like	1089..1430	CDD:199844	105/341 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920