DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18417 and Cpa6

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_038965675.1	Gene:	Cpa6 / 312913	RGDID:	1311764	Length:	290	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	101/291 - (34%)
Similarity:	152/291 - (52%)	Gaps:	25/291 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 RVFLKTVGRSYEGRWLKTITITNGDARRN---KNVILVDGGFHAREWISPAAATYLINQ--LVYN 206
            |||  .:|||:|||.|..|.:    .|::   |..:.:|.|.||||||.||...:.:.:  |.|.
  Rat    13 RVF--PIGRSFEGRSLLIIQL----GRKSQVYKRAVWIDCGIHAREWIGPAFCQWFVKEAILTYK 71

  Fly   207 LEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSS-DCIGTDPNRNFDFHWNEE 269
            .:.....:|: ..:.|:||:|.|||.::...:  |.|||||..:|. .|.|.|.|||:...|.:|
  Rat    72 TDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHD--RFWRKTRSRNSKFHCRGVDANRNWKVKWCDE 134

  Fly   270 GASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWT-AAVPD--- 330
            |||.||||:.|.|..|.||||...|.:.:..:..|.:.||:.|:|..::|||:.:. |.:|:
  Rat   135 GASADPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLYPYSYKHATIPNFSC 199

  Fly   331 TEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGFPISFTMEL-PFGGTG 394
            .|...|:..    .|::...|..|:.||::.|: |.:||.|.|:|:..|.|.||..|| ..|..|
  Rat   200 VEFAAHKAV----KALRSVHGIRYRHGPASQTL-YVSSGNSMDWAYKNGIPYSFAFELRDTGYFG 259

  Fly   395 FDPPASDIDSIVKETWVGIAAMARKVIQKYP 425
            |..|...|.....||.:.:..:...:::..|
  Rat   260 FLLPEMLIKPTCTETMLAVKNITMHLLKNCP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	100/284 (35%)
Cpa6	XP_038965675.1	Peptidase_M14_like	1..289	CDD:416253	100/288 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351660
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850