DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18417 and Cpb1

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_036665.2	Gene:	Cpb1 / 24271	RGDID:	2391	Length:	415	Species:	Rattus norvegicus

Alignment Length:	432	Identity:	148/432 - (34%)
Similarity:	216/432 - (50%)	Gaps:	39/432 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNP-GK 69
            ::|.|:.:|::........::|.::|.||.....  ....:.||...       .|::...| ..
  Rat     1 MLLLLALVSVALAHASEEHFDGNRVYRVSVHGED--HVNLIQELANT-------KEIDFWKPDSA 56

  Fly    70 IMVHPHEQVNF----------VQLMEENNVKYDIINRNVGLTLSRQFETN-RMLRHWFPYNGRLG 123
            ..|.|...|:|          ...:|||.|.|:::..||...|..||::: |...|.:
  Rat    57 TQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSY------- 114

  Fly   124 TERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAR 188
             .:|...|.|..:|:.:|.::|..|....:|.::|||.:..:.|  |..|.||..|.:|.|||||
  Rat   115 -TKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKI--GKTRPNKPAIFIDCGFHAR 176

  Fly   189 EWISPAAATYLINQLV--YNLEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDTRMWRKTRKP-S 249
            ||||||...:.:.:.|  ||.|.:...||| .|:.:|||||.|||.||...:  |||||||.. :
  Rat   177 EWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKD--RMWRKTRSTMA 239

  Fly   250 SSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSY 314
            .|.|:|.||||||:..|.|.|||..||...|.|..|.||.|...:.|.|.:.:...:.|||:|||
  Rat   240 GSSCLGVDPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSY 304

  Fly   315 GSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAG 379
            ..::|||:.:...:|:..|:|:.:.......:....||.|..||.|||| |.|:|.|||::::.|
  Rat   305 SQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTI-YPAAGGSDDWSYDQG 368

  Fly   380 FPISFTMEL-PFGGTGFDPPASDIDSIVKETWVGIAAMARKV 420
            ...|||.|| ..|..||..|.|.|....:||.:.:..:|..|
  Rat   369 IKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	11/44 (25%)
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	120/297 (40%)
Cpb1	NP_036665.2	Propep_M14	33..102	CDD:396700	16/77 (21%)
Cpb1	NP_036665.2	M14_CPB	112..410	CDD:349443	121/310 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351636
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650