DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18417 and W01A8.6

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_492003.2	Gene:	W01A8.6 / 189076	WormBaseID:	WBGene00012168	Length:	380	Species:	Caenorhabditis elegans

Alignment Length:	327	Identity:	100/327 - (30%)
Similarity:	160/327 - (48%)	Gaps:	37/327 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 YYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDAR---RNKNVILVDGGFHAR 188
            |.:..:...:|:.:|.::|..|.|||:||:.|||.|..:.|  |...   :.|..:.:|||.|||
Worm    35 YNDWPQFEDYIKGVAHDNPSFVQLKTIGRTREGRPLLGVRI--GKPALPGKRKIAVWLDGGNHAR 97

  Fly   189 EWISPAAATYLINQLV--YNLEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDT--RMWRKTRKP 248
            ||.:...|.|.|.:||  |..:|.....:: .|..:.||:||||:.|::.|...  |.|||.|.|
Worm    98 EWPAFHVAVYFIEKLVNGYLSDDKITKYVETLDIYVFPVLNPDGFVYSRTSTRAMIRQWRKNRAP 162

  Fly   249 SSSDCIGTDP------------NRNFDFHWNEEG-ASDDPCDNIYAGAKPFSEPEALVVGDLIHS 300
              .:|.||.|            |||:|..::.:. ..::||.:.:.|.:||||||...|.|.|.|
Worm   163 --ENCTGTGPFQTDICCEGVDLNRNYDIGFSHKNYPFNNPCSDEFQGPRPFSEPETRAVRDFIMS 225

  Fly   301 YVDRGQMY--LTLHSYGSLILYPWGW-TAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATT 362
            ....|::|  :::|::|.|.:.|:.: ....|...:||..:|......:.....|.|::|.:|..
Worm   226 SEIYGRLYALVSMHTHGQLWILPYNYQKRTYPQDIKDLEILANRAADRVFAYRETKYRVGTAADM 290

  Fly   363 INYAASGASDDYAFNAGFPISFTMELP------FGGTGFDPPASDIDSIVKETWVGIAAMARKVI 421
            :..|..||:|....|......:.:|||      |   .|......:..|.||||:||..:..:|:
Worm   291 LGTATGGATDWIKKNTPTKYVYVLELPPDMKTWF---AFQVKPHWLIPIGKETWLGIEVIFDQVV 352

  Fly   422 QK 423
            ::
Worm   353 EE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	99/322 (31%)
W01A8.6	NP_492003.2	Zn_pept	35..337	CDD:214748	92/308 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47975
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.830