back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18417 and CPB1

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001862.2	Gene:	CPB1 / 1360	HGNCID:	2299	Length:	417	Species:	Homo sapiens

Alignment Length:	433	Identity:	143/433 - (33%)
Similarity:	224/433 - (51%)	Gaps:	39/433 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPGKI- 70
            :|.|..::|::.......:||.|::.|:.|..:  ....:.||...       ::::...|..:
Human     4 LLVLVTVALASAHHGGEHFEGEKVFRVNVEDEN--HINIIRELAST-------TQIDFWKPDSVT 59

  Fly    71 MVHPHEQVNF----------VQLMEENNVKYDIINRNVGLTLSRQFETN-RMLRHWFPYNGRLGT 124
            .:.||..|:|          ..::::|.::|.::..|:...:..||::. |...|.:
Human    60 QIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSY-------- 116

  Fly   125 ERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHARE 189
            |:|...|.|..:.:.:|.|:|..:....:|.::|||.:..:.:  |.|.:||..|.:|.||||||
Human   117 EKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV--GKAGQNKPAIFMDCGFHARE 179

  Fly   190 WISPAAATYLINQLV--YNLEDNADLLLD-FDWVILPVVNPDGYEYTQLSEDTRMWRKTRKP-SS 250
            |||||...:.:.:.|  |..|.....||| .|:.:|||:|.|||.||...  :|.|||||.. :.
Human   180 WISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTK--SRFWRKTRSTHTG 242

  Fly   251 SDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYG 315
            |.|||||||||||..|.|.|||.:|||..|.|....||.|...:.|.|.:.:...:.|||:|||.
Human   243 SSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYS 307

  Fly   316 SLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGF 380
            .:::||:.:...:.:...:|:.:|.|....:....||.|..||.|||| |.|:|.|||:|::.|.
Human   308 QMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTI-YPAAGGSDDWAYDQGI 371

  Fly   381 PISFTMEL-PFGGTGFDPPASDIDSIVKETWVGIAAMARKVIQ 422
            ..|||.|| ..|..||..|.|.|.:..:||::.|..:|..|::
Human   372 RYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.