Protein Alignment CG18417 and Cpa1

DIOPT Version :10

• Sequence 1: NP_648119.1
• Gene: CG18417 / 38829
• FlyBaseID: FBgn0035780
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_079626.2
• Gene: Cpa1 / 109697
• MGIID: 88478
• Length: 419
• Species: Mus musculus
• Alignment Length: 445
• Identity: 136/445 - (30%)
• Similarity: 218/445 - (48%)
• Gaps: 56/445 - (12%)

  Fly     7 ILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVF------SELNAG 65
            :|.||.| |:|.....| :.|:::..:|      |..||..:.|:.....|..      ....||
Mouse     4 LLVLSVL-LAAVFGNEN-FVGHQVLRIS------ATDEAQVQKVRELEELEHLKLDFWRDPARAG 60

  Fly    66 NPGKIMVHPHEQVNFVQ-LMEENNVKYDIINRNVGLTLSRQ------FETNRMLRHWFPYNGRLG 123
            .|..:.| |...:..|: .:|.:::.|:|:..:|...|..:      |:...:....|.|
Mouse    61 LPIDVRV-PFPTIQSVKAFLEYHDISYEIMIEDVQSLLDEEKQQMSAFQARALSTDAFNY----- 119

  Fly   124 TERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAR 188
             ..|:..:||.:|::.|..|||:.|....:|.::|||.:..:..:.|..  |:..|.:|.|.|:|
Mouse   120 -ATYHTLDEIYEFMDLLVTEHPQLVSKIQIGSTFEGRPINVLKFSTGGT--NRPAIWIDTGIHSR 181

  Fly   189 EWISPAAATYLINQLV--YNLE-------DNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRK 244
            ||::.|:..:...::.  |..|       ||.|:.|:.      |.||||:.||.  :..|||||
Mouse   182 EWVTQASGVWFAKKITKDYGQEPTLTAILDNMDIFLEI------VTNPDGFVYTH--KTNRMWRK 238

  Fly   245 TRK-PSSSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQM- 307
            ||. ...|.|:|.|||||:|..:...|||.:||...|.|..|.||.|...:.|.:.|:   |.:
Mouse   239 TRSHTEGSLCVGVDPNRNWDAAFGMPGASSNPCSETYRGKFPNSEVEVKSIVDFVTSH---GNIK 300

  Fly   308 -YLTLHSYGSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGAS 371
             ::::|||..|:|||:|:|:.....:|:|.::|.:..:|:....||.:|.|....|| |.|||::
Mouse   301 AFISIHSYSQLLLYPYGYTSEPAPDKEELDQLAKSAVTALTSLHGTKFKYGSIIDTI-YQASGST 364

  Fly   372 DDYAFNAGFPISFTMEL-PFGGTGFDPPASDIDSIVKETWVGIAAMARKVIQKYP 425
            .|:.::.|...|||.|| ..|..||..|||.|....:|||:.:..:....: |:|
Mouse   365 IDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTV-KHP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<70..105	CDD:460505	8/35 (23%)
		Peptidase_M14	133..412	CDD:459730	104/291 (36%)
Cpa1	NP_079626.2	Propep_M14	26..100	CDD:460505	17/80 (21%)
		M14_CPA	117..417	CDD:349442	108/320 (34%)