DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18417 and cpa3

DIOPT Version :9

Sequence 1:	NP_648119.1	Gene:	CG18417 / 38829	FlyBaseID:	FBgn0035780	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	XP_031758725.1	Gene:	cpa3 / 100494117	XenbaseID:	XB-GENE-853724	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	435	Identity:	140/435 - (32%)
Similarity:	226/435 - (51%)	Gaps:	45/435 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVWVILALSCLSLSAGLQRTNKYEGYKIYEVSSEARS-VAFSEALSELVKNASYYEVFSELNAGN 66
            ::||:     .|.::.:.....:.|.|::....:... ||....:.|.:|          |:..:
Frog     9 LIWVL-----GSAASAVLAKQTFHGDKVFRAKLQTEGHVALIHKIKEAIK----------LDFWH 58

  Fly    67 PGKI--MVHPHEQVNF---------VQ-LMEENNVKYDIINRNVGLTLSRQF-ETNRMLRHWFPY 118
            |...  || ||.:.:|         || |:::|:|.|:::..::...:..|. .|.:..||.:
Frog    59 PDTADRMV-PHTEADFHVHSDQADSVQILLQQNSVPYEVLFHDLQEGIEAQLNNTKKSKRHSY-- 120

  Fly   119 NGRLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDG 183
                  .:|...|:|.::...|..::|..|....:|:|.|||.:..:.:.|.|:.  ...|.:|.
Frog   121 ------TKYNTWEKIVEWTSKLTKKYPNLVQRIDIGKSVEGRPMYVLQVGNPDSA--TKAIFMDC 177

  Fly   184 GFHAREWISPAAATYLINQLVYNLEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKP 248
            |.|||||||||...:.:.:|:....:..:|:....:.||||.|.|||.:| .:|| |||||.|.|
Frog   178 GIHAREWISPAFCQWFVKELIKGKNNIRELVKSLTFYILPVFNIDGYVWT-WTED-RMWRKNRSP 240

  Fly   249 S-SSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLH 312
            | .:.|:|||.||||:..|.:.|:||:||..||.||...||.|...|...|.|:||..:.|::.|
Frog   241 SEDAKCVGTDLNRNFNISWCDIGSSDEPCSEIYCGAAAESEIETKNVASFIRSHVDSIKAYISFH 305

  Fly   313 SYGSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFN 377
            |:..::|:|:.:|..:....::|.|:|....:.:|...||.|..||||:|| |..:|:|||:|::
Frog   306 SFSQMLLFPFSYTYELAPDHKELDEIAKGAVAELQGLYGTSYTYGPSASTI-YPTAGSSDDWAYS 369

  Fly   378 AGFPISFTMEL-PFGGTGFDPPASDIDSIVKETWVGIAAMARKVI 421
            .|...|||.|| ..|..||..|.|.|.:..:||.:.:|.:|:.|:
Frog   370 LGIKYSFTFELRDEGKKGFLLPQSQIKATCQETTLAVAYIAKYVL 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18417	NP_648119.1	Propep_M14	<65..99	CDD:280416	12/45 (27%)
CG18417	NP_648119.1	M14_CP_A-B_like	127..420	CDD:199844	113/294 (38%)
cpa3	XP_031758725.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920