Protein Alignment CG8562 and ECM14

DIOPT Version :10

• Sequence 1: NP_648118.1
• Gene: CG8562 / 38828
• FlyBaseID: FBgn0035779
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_012000.1
• Gene: ECM14 / 856533
• SGDID: S000001174
• Length: 430
• Species: Saccharomyces cerevisiae
• Alignment Length: 445
• Identity: 116/445 - (26%)
• Similarity: 211/445 - (47%)
• Gaps: 56/445 - (12%)

  Fly     5 LGLLVLFLGATLVAAEQDYEGYRIY------------EVIPSTADQADLLHQLSLQGYDFISETR 57
            |.:|:...|| :...::||..|.:|            :||....|..|:.    .:..:||.
Yeast    12 LFVLLAVTGA-VQGLQEDYSEYAVYRFTSDNYSTLVRDVIAPLTDDYDVW----TRSNNFID--- 68

  Fly    58 LLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQ-RLLAPITGKGRLST 121
                    |..|.::.  :|:.:.:     ::..|:...|.......||. |..|..........
Yeast    69 --------IKLPKEIG--EQINDGQ-----VIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFF 118

  Fly   122 ERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKAN--KKVIFMDGGFHA 184
            ..|...:.|..::|.|.:.|||.|.|:.:|.::|.|.||.:.|:....::|  ||.|.:.||.||
Yeast   119 NEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNPEKKTIVITGGIHA 183

  Fly   185 REWISPAAVLYVIDQLVEQF---EENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPY 246
            |||||.:.|.:.:.||:.::   ::....|.|.|::::|:.|.|||.:|.:..  |:|||.|| .
Yeast   184 REWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYTWSHD--RLWRKNRQ-R 245

  Fly   247 TYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPE-TITVRDLMHSLADRGIM-YL 309
            |:..| |.|.|.:.:|.|.|  |.|.::.|::.|:|.|.|...| :...:.:..:..|..|. |:
Yeast   246 THVPQ-CLGIDIDHSFGFQW--EKAHTHACSEEYSGETPFEAWEASAWYKYINETKGDYKIYGYI 307

  Fly   310 TLHSYGNYLLYPWGWTSD-LPENWEDLDAVARTGAEAIENATGTVYTYGSS-----TNVL-YIAA 367
            .:|||...:|||:.::.| ||.:.|:|..::...::||.:.:|..|...|:     :::. .:.|
Yeast   308 DMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGA 372

  Fly   368 GASDDYGYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIE 422
            |::.|:.|:...:.:..::|...|:.||..|...|.....||:..::...:.:::
Yeast   373 GSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPVGKETYAALKYFCDFLLD 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	29..100	CDD:460505	12/82 (15%)
		Peptidase_M14	130..412	CDD:459730	92/295 (31%)
ECM14	NP_012000.1	M14_CP_A-B_like	121..425	CDD:349433	93/309 (30%)