DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and Agbl4

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011238954.1	Gene:	Agbl4 / 78933	MGIID:	1918244	Length:	552	Species:	Mus musculus

Alignment Length:	330	Identity:	77/330 - (23%)
Similarity:	123/330 - (37%)	Gaps:	85/330 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 YTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDG---KANKKVIFMDGGFHARE 186
            ||:....:|:|.|.::.....|.:.:|.|.:||.|..:|||:.:.   .:.|||||:.|..|..|
Mouse   181 YTYTRFQHYLDSLQKKNMDYFFREQLGQSVQQRQLDLLTITSPENLREGSEKKVIFITGRVHPGE 245

  Fly   187 WISPAAVLYVIDQLVEQFEENAHLLKDY-DWVILPLVNADG-----YEHTQTG-TLARMWRKTRQ 244
            ..|......:||.||.| ...|.:|::: .:.|.|::|.||     |..:..| .|.|.|   ..
Mouse   246 TPSSFVCQGIIDFLVSQ-HPIARVLREHLVFKIAPMLNPDGVYLGNYRCSLMGFDLNRHW---LD 306

  Fly   245 PYTYAGQTCYGA---------DPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHS 300
            |..:|..|.:|.         ||..:.:|:           .|.:|                 ||
Mouse   307 PSPWAHPTLHGVKQLIIKMYNDPKTSLEFY-----------IDIHA-----------------HS 343

  Fly   301 LADRGIMYLTLHSYGNYL----------LYPWGWTSDLPENWEDLDAVART-GAEAIENATGTVY 354
            ....|.|      |||..          ::|    ..|.:|.||....:.: ..:|::..||..:
Mouse   344 TMMNGFM------YGNIFEDEERFQRQSIFP----KLLCQNAEDFSYTSTSFNRDAVKAGTGRRF 398

  Fly   355 TYGSSTNVLYIAAGASDDYGYYAGFNVSITMELP----GAGSIGFNPPVTRIDEFVTETWIGIRA 415
            ..|...:..|........|.|..|   ..|..:|    ....:|.|...|.:|      :..:.:
Mouse   399 LGGLLDHSSYCYTLEVSFYSYIIG---GTTAAVPYTEEAYMKLGRNVARTFLD------YYRLNS 454

  Fly   416 MAEKV 420
            :.||:
Mouse   455 LVEKI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	76/328 (23%)
Agbl4	XP_011238954.1	Pepdidase_M14_N	65..>142	CDD:375499
Agbl4	XP_011238954.1	M14_AGBL4_like	199..450	CDD:349479	70/301 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810