DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and cpb2

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001025617.1	Gene:	cpb2 / 595005	XenbaseID:	XB-GENE-969491	Length:	421	Species:	Xenopus tropicalis

Alignment Length:	448	Identity:	134/448 - (29%)
Similarity:	216/448 - (48%)	Gaps:	65/448 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLVLFLGATLV-----AAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLGHPSRVI 66
            |::..||..:|     |.:.|    ::..|:|.|..|.::|..::.|             |..|:
Frog     5 LIICILGLFVVDFQVSAEDSD----QVLYVLPRTDQQVEILKNITSQ-------------PEIVL 52

  Fly    67 VSPAQLKHFQ-------------------QLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAP 112
            ..|...:|..                   :|.|:..:.:.|||:      |:|..::|...
Frog    53 WKPDSNEHIMKNKEVHFYVNESFIDTVKAELNESSILYMVLVNN------AQELIEQQTFN---- 107

  Fly   113 ITGKGRLST---ERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKK 174
            .|...|.:|   |:|:|.|:|..::..:.::....:....:|:|:|.|.|..:.: :|..|..|.
Frog   108 DTSNQRSATSFYEQYHTLEDIYYWMQHMVEKHSDMLQRIHIGYSFENRPLYVLKV-SGKEKTAKH 171

  Fly   175 VIFMDGGFHAREWISPAAVLYVIDQLVEQFEEN---AHLLKDYDWVILPLVNADGYEHTQTGTLA 236
            .:::|.|.|||||||||..|:.:...||.:..:   ..||:..|:.|||::|||||:.:.|.. .
Frog   172 AVWIDCGIHAREWISPAFCLWFVGHAVEYYGVDLSMTKLLRYLDFYILPVMNADGYQFSWTAK-N 235

  Fly   237 RMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLM--H 299
            |||||.|..||.:  .|.|.|.|||||..|...||||:||.:.|.||.|.||||...|...:  |
Frog   236 RMWRKNRSKYTKS--NCIGTDLNRNFDAGWCGPGASSDPCHEIYCGPYAESEPEVSAVVSFLKKH 298

  Fly   300 SLADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLY 364
            ....:|  |:|:|||...:|:|:.:|:...::.::|..:::..||.|.:.:...|.||:....:|
Frog   299 QNVVKG--YITVHSYSQMVLFPYSYTNKKSKDHDELLLLSKKVAEGIRSTSRNKYMYGAGAETIY 361

  Fly   365 IAAGASDDYGYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIE 422
            :|.|.|||:.|..|...|.|.||...|..||..|...|....:|....::.:|..:::
Frog   362 LAPGGSDDWAYDLGIKYSFTFELRDKGMYGFLLPPQLIKPTCSEGITAVKIIAAHIVK 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	15/87 (17%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	106/300 (35%)
cpb2	NP_001025617.1	Propep_M14	33..104	CDD:366995	15/89 (17%)
cpb2	NP_001025617.1	M14_CPB2	118..418	CDD:349465	107/305 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920