DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and CG4408

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_651141.2	Gene:	CG4408 / 42762	FlyBaseID:	FBgn0039073	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	124/393 - (31%)
Similarity:	198/393 - (50%)	Gaps:	34/393 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YEGYRIYEVIPSTADQADLLHQLSLQGYD---FISETRLLGHPSRVIVSPAQLKHFQQLVEAEKM 84
            |:..|||:|..::.:...|...|. |..|   |:...|..|....::|:.|::..|..||.:..:
  Fly    81 YDHTRIYQVELASEEHVRLFQALE-QASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNV 144

  Fly    85 TLTLVNSNLGASIAEEFAQRQMQRLLAP-ITGKGRLSTERYYTHEEIINYIDDLAQRFPSRVFVK 148
            |..::|.|..|.|...:.:      :|| .|.......:||:..|.|..::..||:..|..:.|:
  Fly   145 THRVLNYNFQALIDANYLE------VAPEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVE 203

  Fly   149 TVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEENAH-LLK 212
             :|.|.:.|.:..:.|...:  .|:..:|::.|.||||||:||...|:|||||...:.... |.:
  Fly   204 -LGVSAQGRPILGVQIAFDN--ENRTTVFVESGIHAREWIAPATATYIIDQLVNSKDSAVQALAR 265

  Fly   213 DYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCA 277
            ...|.|.|.||.|||::|..|.  |||||.|..:    ..|.|.|.||||.||||..|||.:||.
  Fly   266 SQRWYIFPTVNPDGYQYTFKGD--RMWRKNRALF----GICRGVDLNRNFPFHWNVTGASGDPCR 324

  Fly   278 DTYAGPTAFSEPET-ITVRDLMHSL-ADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVAR 340
            ..|:||:|.||.|| ..:..:.|.: ::|...:::||||...:::|:|.:::..:|:.||..:.:
  Fly   325 YDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGK 389

  Fly   341 TGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITM--ELPGAGSIGFNPPVTRID 403
            ..|..|::.:|.:|..||....:|.::|.|.|:. :....:.||.  ||.|        |....|
  Fly   390 LAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWA-HGQLKIPITFSYELRG--------PADSED 445

  Fly   404 EFV 406
            .|:
  Fly   446 LFI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	18/71 (25%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	98/288 (34%)
CG4408	NP_651141.2	Propep_M14	88..159	CDD:280416	18/71 (25%)
CG4408	NP_651141.2	M14_CP_A-B_like	179..472	CDD:199844	98/288 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466971
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750