DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8562 and CG14820

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	145/428 - (33%)
Similarity:	231/428 - (53%)	Gaps:	34/428 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLVLFLGATLVAAEQ-DYEGYRIYEVIPSTADQADLLH----QLSLQGYDFISETRLLGHPSRVI 66
            |||:.|.....:.|| .|:.|::|.|.....:|..|||    .|.|..:   .|.|.||..|.::
  Fly     6 LLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSW---REARHLGESSDIM 67

  Fly    67 VSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHEEII 131
            :.|...|.|:.|:.....|..|...|:...|.   |||..||:.:       :...:::|.|||.
  Fly    68 LPPEYQKTFESLLTKHNFTYNLKIDNVQTHID---AQRPKQRITS-------MEWTQFHTLEEIY 122

  Fly   132 NYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYV 196
            .::|.:..|:|..|...|:|.|||.|.::.:.|:..:|   ...:|::...||||||:.|.:.|.
  Fly   123 AWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEG---NPAVFIESNIHAREWITSATITYF 184

  Fly   197 IDQ-LVEQFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNR 260
            ||: ||.:......:.::.||.|:|::|.||:.::.  .:.|:|||:|.|....|: |.|.|.||
  Fly   185 IDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSH--EVERLWRKSRLPSDPTGE-CIGTDLNR 246

  Fly   261 NFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGI--MYLTLHSYGNYLLYPWG 323
            |||:.|...||.|:||:..||||:..|:||...:...:::....|.  :|::|||||.|:|.|||
  Fly   247 NFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWG 311

  Fly   324 WTS-DLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSI--TM 385
            .|: :.||::..:..||:..::|:....|||:|||||...||..:|:..::. ||..|:.|  |:
  Fly   312 HTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWA-YAVKNIKIHYTI 375

  Fly   386 ELPGAGSIGF-NPP--VTRIDEFVTETWIGIRAMAEKV 420
            ||...|.:|| .||  :..:...|||.::|:.|.|.::
  Fly   376 ELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREI 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	20/72 (28%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	111/304 (37%)
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	20/74 (27%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	110/301 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466980
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750