DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and CG32379

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_729252.2	Gene:	CG32379 / 326211	FlyBaseID:	FBgn0052379	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	159/332 - (47%)
Similarity:	219/332 - (65%)	Gaps:	21/332 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 LAPITGKGRLSTER---------------YYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVL 159
            |||:....|....|               :|||.||.:|:|.|.:|||.||.||..|||||:|.|
  Fly    15 LAPLVHAQRAENLRKKLLIQWPHIDVLSAFYTHSEINDYLDSLLERFPKRVQVKQFGWSYERRPL 79

  Fly   160 KTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEENAHLLKDYDWVILPLVNA 224
            |.:|||||||:.||.||.:||..||||||||:..||:|.||::.:.:|..||:||||||:|:|||
  Fly    80 KVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNYGDNQELLQDYDWVIMPVVNA 144

  Fly   225 DGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHW-NEEGASSNPCADTYAGPTAFSE 288
            ||||:|.|.  :|.|||:|:|  .:...|.|.|.||||.:.| ::||:||:||.:.|.|...|.:
  Fly   145 DGYEYTHTD--SRYWRKSRRP--TSNPECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQ 205

  Fly   289 PETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTV 353
            .|:..:||:|.....|...||:|||||||.|.|||:|||.|:.::|:.:||..||:||..:|..:
  Fly   206 SESQVLRDVMLHYKGRLNFYLSLHSYGNYFLLPWGYTSDFPDTYQDMMSVADAGAKAIIYSTNGI 270

  Fly   354 YTYGSSTNVLYIAAGASDDYGY-YAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMA 417
            |:|||:..|||..:|.:.|:.: .....|::|||||.||..||:|.:::|:..|||:|:|:||||
  Fly   271 YSYGSTYYVLYPTSGDTTDFAFGVVNATVAMTMELPAAGFQGFDPWISQIERLVTESWVGVRAMA 335

  Fly   418 EKVIEMY 424
            .:||..|
  Fly   336 AEVIRRY 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	151/297 (51%)
CG32379	NP_729252.2	M14_CP_A-B_like	44..338	CDD:199844	151/297 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450339
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	1	1.000	-	-		H76534
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.850