DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8562 and CG3108

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_572262.1	Gene:	CG3108 / 31506	FlyBaseID:	FBgn0029807	Length:	1132	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	144/423 - (34%)
Similarity:	221/423 - (52%)	Gaps:	58/423 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YEGYRIYEVIPST------ADQADLLHQLSL-----QGYDFISETRLL---------GHPSRVIV 67
            |:|.:::.::..|      ||:....:...|     |..|::.:.::|         .:.||:::
  Fly   723 YDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVL 787

  Fly    68 SPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKG-RLSTERYYTHEEII 131
                :.:.|:::|.|...            ||:.|:.|.:        || ||:.:.|:..|:|.
  Fly   788 ----IDNLQRVIEKENPP------------AEKIAELQNR--------KGHRLTWQAYHRLEDIH 828

  Fly   132 NYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYV 196
            .:||.:|:.:|.....:.:|:|.|:|.||.:.|:||:  |....|::|||.|||||||||.|.|:
  Fly   829 GFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGN--ARNPGIWIDGGMHAREWISPATVTYI 891

  Fly   197 IDQLVEQFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRN 261
            .:||||.:|:....::..:|.|.|:.|.||||::.  |..|:|||..:.:   |:.|.|.|.|||
  Fly   892 ANQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSH--TTDRLWRKNMRAH---GRQCPGVDLNRN 951

  Fly   262 FDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIM-YLTLHSYGNYLLYPWGWT 325
            |.:.|..:|.|::||:.||.|..|||||||..:...:......... ||:.||||.|:|||||:.
  Fly   952 FGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYD 1016

  Fly   326 SDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGY-YAGFNVSITMELPG 389
            ..|.::..|||.|||....:|..:||..||.|||...||.|||.|||:.. .||...:.|:|:..
  Fly  1017 YQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGD 1081

  Fly   390 AGSIGFNPPVTRID----EFVTETWIGIRAMAE 418
            .|..||..|...|.    :.||......||:|:
  Fly  1082 TGRYGFVLPARFIQYNGKDGVTFADTVARAIAQ 1114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	12/88 (14%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	122/301 (41%)
CG3108	NP_572262.1	Propep_M14	730..797	CDD:280416	10/70 (14%)
CG3108	NP_572262.1	M14_CP_A-B_like	821..1112	CDD:199844	120/297 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466928
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.750