DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and CG42264

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_572260.2	Gene:	CG42264 / 31504	FlyBaseID:	FBgn0259149	Length:	634	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	114/442 - (25%)
Similarity:	197/442 - (44%)	Gaps:	68/442 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QDYEGYRIYEVIPSTADQADL----------LHQLSLQGYDFISETR----------LLGHPSRV 65
            |.|.|:::::|..:..:|.:|          :..::..|.|.:.|.|          .:|:...:
  Fly   218 QRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNI 282

  Fly    66 IVSPAQLKHFQQLVE--AEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHE 128
            ::...:....:..||  |.:..|..|.:|            .:..:..|   ...::..||:...
  Fly   283 MIDDIESAIDESYVEVPAVEHPLDSVRNN------------SLPWMEVP---GSTMNWRRYHDQA 332

  Fly   129 EIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAV 193
            :|..::..|.:.:...|.:..:|.:..:|.|:.|.::||:  .:...:|:|.|..||:|:||||:
  Fly   333 DIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGN--PDNWAVFVDAGLQARDWLSPAAL 395

  Fly   194 LYVIDQLVE-------------QFEENAH-LLKDYDWVILPLVNADGYEHT-QTGTLARMWRKTR 243
            .|.|.:|..             |.:..|. .::..||..|||.|.|||::: ||.   |:|.|.|
  Fly   396 TYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTD---RLWTKNR 457

  Fly   244 QPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMY 308
            ...:.:|  |||.:.:||||:.|:..|::||||.:.|.|..:|||||:..|...:..:.:....|
  Fly   458 GYDSVSG--CYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMREYLGAY 520

  Fly   309 LTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDY 373
            ::|..||..:.||||....:.||..:|...||....|:.......|:.|:|........|.|.|:
  Fly   521 VSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYRQKLARPGNSADW 585

  Fly   374 -----GYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKV 420
                 |....||    |.|...|..|:..|...|.|...|.:..:|.:|:::
  Fly   586 VQDRIGPQLVFN----MFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIAQQL 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	14/90 (16%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	95/315 (30%)
CG42264	NP_572260.2	Propep_M14	<241..293	CDD:280416	5/51 (10%)
CG42264	NP_572260.2	M14_CP_A-B_like	328..633	CDD:199844	95/315 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467000
Domainoid	1	1.000	166	1.000	Domainoid score	I805
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.850