Protein Alignment CG8562 and CPB2

DIOPT Version :10

• Sequence 1: NP_648118.1
• Gene: CG8562 / 38828
• FlyBaseID: FBgn0035779
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001863.3
• Gene: CPB2 / 1361
• HGNCID: 2300
• Length: 423
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 130/424 - (30%)
• Similarity: 215/424 - (50%)
• Gaps: 25/424 - (5%)

  Fly     8 LVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLGHP--SRVIVSPA 70
            :|||....:.|    ::..::...:|.|:.|..:|..|:.. |:.:     |..|  :.:||...
Human    12 IVLFCEQHVFA----FQSGQVLAALPRTSRQVQVLQNLTTT-YEIV-----LWQPVTADLIVKKK 66

  Fly    71 QLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLST---ERYYTHEEIIN 132
            |:..|....:.:.:...|..|.:..|:.....:..:|:.::..|...|.|.   |:|::..||.:
Human    67 QVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYS 131

  Fly   133 YIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVI 197
            :|:.:.:|.|..:....:|.|:|:..|..:.: :|..:|.|..|::|.|.|||||||||..|:.|
Human   132 WIEFITERHPDMLTKIHIGSSFEKYPLYVLKV-SGKEQAAKNAIWIDCGIHAREWISPAFCLWFI 195

  Fly   198 DQLVEQF---EENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPN 259
            ..:.:.:   .:..:||:..|:.::|:||.|||:::....  |||||.|.  .||...|.|.|.|
Human   196 GHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKN--RMWRKNRS--FYANNHCIGTDLN 256

  Fly   260 RNF-DFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWG 323
            ||| ..||.||||||:.|::||.|....||||...|...:....::...|:::|||..::::|:.
Human   257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYS 321

  Fly   324 WTSDLPENWEDLDAVARTGAEAIEN-ATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITMEL 387
            :|....::.|:|..||.....|||. :..|.||:|..:..||:|.|..||:.|..|...|.|:||
Human   322 YTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386

  Fly   388 PGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVI 421
            ...|:.||..|...|.....|.:..:..:|..||
Human   387 RDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	29..100	CDD:460505	15/72 (21%)
		Peptidase_M14	130..412	CDD:459730	101/286 (35%)
CPB2	NP_001863.3	Propep_M14	33..105	CDD:460505	16/77 (21%)
		M14_CPB2	119..420	CDD:349465	105/305 (34%)