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Protein Alignment CG8562 and CPB2

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001863.3	Gene:	CPB2 / 1361	HGNCID:	2300	Length:	423	Species:	Homo sapiens

Alignment Length:	424	Identity:	130/424 - (30%)
Similarity:	215/424 - (50%)	Gaps:	25/424 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLGHP--SRVIVSPA 70
            :|||....:.|    ::..::...:|.|:.|..:|..|:.. |:.:     |..|  :.:||...
Human    12 IVLFCEQHVFA----FQSGQVLAALPRTSRQVQVLQNLTTT-YEIV-----LWQPVTADLIVKKK 66

  Fly    71 QLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLST---ERYYTHEEIIN 132
            |:..|....:.:.:...|..|.:..|:.....:..:|:.::..|...|.|.   |:|::..||.:
Human    67 QVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYS 131

  Fly   133 YIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVI 197
            :|:.:.:|.|..:....:|.|:|:..|..:.: :|..:|.|..|::|.|.|||||||||..|:.|
Human   132 WIEFITERHPDMLTKIHIGSSFEKYPLYVLKV-SGKEQAAKNAIWIDCGIHAREWISPAFCLWFI 195

  Fly   198 DQLVEQF---EENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPN 259
            ..:.:.:   .:..:||:..|:.::|:||.|||:::....  |||||.|.  .||...|.|.|.|
Human   196 GHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKN--RMWRKNRS--FYANNHCIGTDLN 256

  Fly   260 RNF-DFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWG 323
            ||| ..||.||||||:.|::||.|....||||...|...:....::...|:::|||..::::|:.
Human   257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYS 321

  Fly   324 WTSDLPENWEDLDAVARTGAEAIEN-ATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITMEL 387
            :|....::.|:|..||.....|||. :..|.||:|..:..||:|.|..||:.|..|...|.|:||
Human   322 YTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386

  Fly   388 PGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVI 421
            ...|:.||..|...|.....|.:..:..:|..||
Human   387 RDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI 420

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.