Protein Alignment CG8562 and CPA3

DIOPT Version :9

• Sequence 1: NP_648118.1
• Gene: CG8562 / 38828
• FlyBaseID: FBgn0035779
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001861.2
• Gene: CPA3 / 1359
• HGNCID: 2298
• Length: 417
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 127/428 - (29%)
• Similarity: 203/428 - (47%)
• Gaps: 30/428 - (7%)

  Fly     7 LLVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLS-LQGYDF--------ISETRLLGHP 62
            |.|..:..||..|...::..:::.|.|....|||::..|: ....||        ::...::...
Human     5 LPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFR 69

  Fly    63 SRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTH 127
                ||..:.:..|..::..||...::..:|...|.::|..::        ...||.|..:|...
Human    70 ----VSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKE--------DIPGRHSYAKYNNW 122

  Fly   128 EEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAA 192
            |:|:.:.:.:..::|..|....:|.:.|...|..:.|  |:....:|.||.|.|.|||||:|||.
Human   123 EKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKI--GEKNERRKAIFTDCGIHAREWVSPAF 185

  Fly   193 VLYVIDQLVEQFEEN---AHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCY 254
            ..:.:.|..:.:..|   ..||...::.|||:.|.|||  ..:.|..|||||.|.  ......|.
Human   186 CQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGY--IWSWTKNRMWRKNRS--KNQNSKCI 246

  Fly   255 GADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLL 319
            |.|.||||:..||....:::||||.|.|....||.||..|.:.:.|..:...:|:|.|||...||
Human   247 GTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLL 311

  Fly   320 YPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSIT 384
            :|:|:||.||.|.|||..||:.|.:.:.....|.|.||...:.:|..:|:|.|:.|..|...:..
Human   312 FPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFA 376

  Fly   385 MELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIE 422
            .||...|..||..|.:||.....||.:.::.:|:.:::
Human   377 FELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	15/77 (19%)
		M14_CP_A-B_like	124..420	CDD:199844	103/298 (35%)
CPA3	NP_001861.2	Propep_M14	28..102	CDD:280416	15/77 (19%)
		M14_CPB	114..413	CDD:199852	104/304 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750