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Protein Alignment CG8562 and CPA2

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	427	Identity:	133/427 - (31%)
Similarity:	220/427 - (51%)	Gaps:	31/427 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVLFLGATL--VAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGY---DFISETRLLGHPSRVIV 67
            |:||.||..  :...:.:.|.::.|::||..:|...|.||..|.:   ||.......|..:.|.|
Human     5 LILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRV 69

  Fly    68 SPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEE----FAQRQMQRLLAPITGKGRLSTERYYTHE 128
            ....::..:..:|::.:..:::..::...:.:|    ...|:.:|       .|..:...|:|.|
Human    70 PFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRER-------SGNFNFGAYHTLE 127

  Fly   129 EIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAV 193
            ||...:|:|....|..|....:|.|:|.|.:..:..:.|   .:|..|::|.|.|||||::.|..
Human   128 EISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG---GDKPAIWLDAGIHAREWVTQATA 189

  Fly   194 LYVIDQLVEQFEEN---AHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYG 255
            |:..:::|..:.::   ..:|...|..:||:.|.|||..:||..  |||||||.  ..:|..|.|
Human   190 LWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKN--RMWRKTRS--KVSGSLCVG 250

  Fly   256 ADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIM--YLTLHSYGNYL 318
            .|||||:|..:...|||||||:|:|.||:|.||.|..::.|.:.|   .|.:  ::|||||...|
Human   251 VDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS---HGKVKAFITLHSYSQLL 312

  Fly   319 LYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSI 383
            ::|:|:.....:::::|..||:..|:::.:..||.|..|...:|:|.|:|.|.|:.|..|...|.
Human   313 MFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSF 377

  Fly   384 TMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKV 420
            ..||...|..||..|..:|.....|||:|::|:.|.|
Human   378 AFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.