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Protein Alignment CG8562 and CPA1

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001859.1	Gene:	CPA1 / 1357	HGNCID:	2296	Length:	419	Species:	Homo sapiens

Alignment Length:	428	Identity:	128/428 - (29%)
Similarity:	219/428 - (51%)	Gaps:	27/428 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GLLVL--FLGATLVAAEQDYEGYRIYEVIPSTADQADL-----LHQLSLQGYDFISETRLLGHPS 63
            |||||  .|||  |..::|:.|:::..:  |.||:|.:     |..|.....||.......|.|.
Human     3 GLLVLSVLLGA--VFGKEDFVGHQVLRI--SVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPI 63

  Fly    64 RVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHE 128
            .|.|....::..:..:|:..::...:..::.:.:.||  |.||....:........:...|:|.|
Human    64 DVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEE--QEQMFAFRSRARSTDTFNYATYHTLE 126

  Fly   129 EIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAV 193
            ||.:::|.|....|..|....:|.:||.|.:..:..:.|..|  :..|::|.|.|:|||::.|:.
Human   127 EIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSK--RPAIWIDTGIHSREWVTQASG 189

  Fly   194 LYVIDQLVEQFEENA---HLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYG 255
            ::...::.:.:.::|   .:|...|..:..:.|.||:..|.:..  |||||||. :| ||..|.|
Human   190 VWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTN--RMWRKTRS-HT-AGSLCIG 250

  Fly   256 ADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIM--YLTLHSYGNYL 318
            .|||||:|..:...|||||||::||.|..|.||.|   |:.::..:.|.|.:  ::::|||...|
Human   251 VDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVE---VKSIVDFVKDHGNIKAFISIHSYSQLL 312

  Fly   319 LYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSI 383
            :||:|:.::...:.::||.:::....|:.:..||.:.|||....:|.|:|::.|:.|..|...|.
Human   313 MYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSF 377

  Fly   384 TMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVI 421
            |.||...|..||..|.::|.....|||:.:..:.|..:
Human   378 TFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.