DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and cpa3

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_031758725.1	Gene:	cpa3 / 100494117	XenbaseID:	XB-GENE-853724	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	132/421 - (31%)
Similarity:	205/421 - (48%)	Gaps:	20/421 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVLFLG--ATLVAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLG--HPSRV--I 66
            |:..||  |:.|.|:|.:.|.:::.....|.....|:|:        |.|...|.  ||...  :
Frog     9 LIWVLGSAASAVLAKQTFHGDKVFRAKLQTEGHVALIHK--------IKEAIKLDFWHPDTADRM 65

  Fly    67 VSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHEEII 131
            |...:........:|:.:.:.|..:::...:.....|..::..|.......|.|..:|.|.|:|:
Frog    66 VPHTEADFHVHSDQADSVQILLQQNSVPYEVLFHDLQEGIEAQLNNTKKSKRHSYTKYNTWEKIV 130

  Fly   132 NYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYV 196
            .:...|.:::|:.|....:|.|.|.|.:..:.:.|.|...  |.||||.|.|||||||||...:.
Frog   131 EWTSKLTKKYPNLVQRIDIGKSVEGRPMYVLQVGNPDSAT--KAIFMDCGIHAREWISPAFCQWF 193

  Fly   197 IDQLVEQFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRN 261
            :.:|::.......|:|...:.|||:.|.|||  ..|.|..|||||.|.|...|  .|.|.|.|||
Frog   194 VKELIKGKNNIRELVKSLTFYILPVFNIDGY--VWTWTEDRMWRKNRSPSEDA--KCVGTDLNRN 254

  Fly   262 FDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWGWTS 326
            |:..|.:.|:|..||::.|.|..|.||.||..|...:.|..|....|::.||:...||:|:.:|.
Frog   255 FNISWCDIGSSDEPCSEIYCGAAAESEIETKNVASFIRSHVDSIKAYISFHSFSQMLLFPFSYTY 319

  Fly   327 DLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITMELPGAG 391
            :|..:.::||.:|:.....::...||.||||.|.:.:|..||:|||:.|..|...|.|.||...|
Frog   320 ELAPDHKELDEIAKGAVAELQGLYGTSYTYGPSASTIYPTAGSSDDWAYSLGIKYSFTFELRDEG 384

  Fly   392 SIGFNPPVTRIDEFVTETWIGIRAMAEKVIE 422
            ..||..|.::|.....||.:.:..:|:.|::
Frog   385 KKGFLLPQSQIKATCQETTLAVAYIAKYVLD 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416	11/72 (15%)
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	108/295 (37%)
cpa3	XP_031758725.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920