DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8562 and cpo

DIOPT Version :9

Sequence 1:	NP_648118.1	Gene:	CG8562 / 38828	FlyBaseID:	FBgn0035779	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001139101.1	Gene:	cpo / 100005630	ZFINID:	ZDB-GENE-070619-6	Length:	363	Species:	Danio rerio

Alignment Length:	301	Identity:	104/301 - (34%)
Similarity:	160/301 - (53%)	Gaps:	5/301 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 RYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREW 187
            :|:|.:||..:::.:.:..|..|...|.|.:||:|.:..:.| .......||.|:||.|.|||||
Zfish    34 KYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKI-GFSSTTPKKAIWMDCGIHAREW 97

  Fly   188 ISPAAVLYVIDQLVEQFEENAH---LLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYA 249
            |:||...:.:.:::..::.::.   |.|:.|:.|.|::|.|||.::......|:|||:|.| .:.
Zfish    98 IAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSP-CHE 161

  Fly   250 GQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSY 314
            ..||.|.|.||||..:|...|.|.|.|::.|.|.||.||||...|.|.:.:..:..:.|||:|||
Zfish   162 NSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLTIHSY 226

  Fly   315 GNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGF 379
            |..:|.|:|..:....|:::|..|....|:||:...|..|..|||.:|||..:|:|.|:....|.
Zfish   227 GQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRDFARLIGI 291

  Fly   380 NVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKV 420
            ..|.|.||...|..||..|..:|.....|.:.|..::...|
Zfish   292 PYSFTFELRDEGQHGFILPEDQIQPTCQEAYEGAMSIINYV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8562	NP_648118.1	Propep_M14	30..99	CDD:280416
CG8562	NP_648118.1	M14_CP_A-B_like	124..420	CDD:199844	103/298 (35%)
cpo	NP_001139101.1	M14_CP_A-B_like	35..332	CDD:199844	103/298 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593450
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850