DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8563 and Cpn1

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_011245709.1	Gene:	Cpn1 / 93721	MGIID:	2135874	Length:	463	Species:	Mus musculus

Alignment Length:	307	Identity:	78/307 - (25%)
Similarity:	132/307 - (42%)	Gaps:	46/307 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 FSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSIS----LNSRVRPRRVAYIQAA 203
            |.|: ||.:::..:..:..:.|...|..::|||.:||::..|..|    ::..:.| .|.|: ..
Mouse    23 FRHH-RYDDLVRTLYKVHNQCPDITRLYNIGRSVKGRYLYVLEFSDYPGIHEPLEP-EVKYV-GN 84

  Fly   204 THGREWITTQTVL----YLAYELLSNLRAFTRVLQDVEIFLVPLVNPDGYE----YTHTTDRFWR 260
            .||.|.:..:.:|    :|..|..:..:...|::||..|.::|.:||||||    ..|:......
Mouse    85 MHGNEVLGRELLLQLSEFLCEEFRNRNQRILRLIQDTRIHILPSMNPDGYEVAAAQVHSPREGPN 149

  Fly   261 KNRHRYAGHSCSGVDINRNFGN-----HWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNR 320
            .:.:....::.:|||:||||.:     ::|.:....|....:........||||.||::::. :.
Mouse   150 MSGYLVGRNNANGVDLNRNFPDLNTYFYYNSKNGGPNHHLPLPDNWKSQVEPETRAVIQWIR-SL 213

  Fly   321 NRVKLSLDVHSFGKFIFYPYGYA-----------KNTVPP------TVGTLRSVA---LRAANQI 365
            |.| ||.::|.......|||..:           .|:..|      |:..:.|.|   :......
Mouse   214 NFV-LSANMHGGAVVANYPYDKSLEHRFRGPHRTSNSPTPDDELFQTLAKVYSYAHGWMHQGWNC 277

  Fly   366 GRYRGTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPGDEF 412
            |.|.....|.|.|   .|..|..:.||.|.:... ...||||..|:|
Mouse   278 GDYFPDGITNGAS---WYSLSKGMQDFNYLHTNC-FEITLELSCDKF 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	76/304 (25%)
Cpn1	XP_011245709.1	Peptidase_M14_like	25..343	CDD:386095	77/305 (25%)
Cpn1	XP_011245709.1	Peptidase_M14NE-CP-C_like	347..421	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4063
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.860