Protein Alignment CG8563 and ECM14

DIOPT Version :10

• Sequence 1: NP_648116.2
• Gene: CG8563 / 38826
• FlyBaseID: FBgn0035777
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_012000.1
• Gene: ECM14 / 856533
• SGDID: S000001174
• Length: 430
• Species: Saccharomyces cerevisiae
• Alignment Length: 463
• Identity: 123/463 - (26%)
• Similarity: 199/463 - (42%)
• Gaps: 97/463 - (20%)

  Fly    16 LAGLGIANNLAGYEGYTKYTVQHGDENAFKYMV-DL---QTNDAELDFWLLTRNSSVLTVSPRRK 76
            ||..|....|  .|.|::|.|.....:.:..:| |:   .|:|  .|.|  ||:::.:.:...::
Yeast    16 LAVTGAVQGL--QEDYSEYAVYRFTSDNYSTLVRDVIAPLTDD--YDVW--TRSNNFIDIKLPKE 74

  Fly    77 TQFEASLSSLGVS------YEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPRRRT 135
            ...:.:...:.:.      ....|..::||..||   ..:::||
Yeast    75 IGEQINDGQVIIDNMNELIQNTLPTSQMMAREQA---VFENDYD--------------------- 115

  Fly   136 RRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRP-----R 195
                 .||:.|.....:..::..|...:|.....|.|||:.|||.:.||.||.|   :|     :
Yeast   116 -----FFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGN---KPESNPEK 172

  Fly   196 RVAYIQAATHGREWITTQTVLYLAYELLS---NLRAFTRVLQDVEIFLVPLVNPDGYEYTHTTDR 257
            :...|....|.||||:..||.:..|:||:   :.:..|:.|.|::..::|:.|||||.||.:.||
Yeast   173 KTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYTWSHDR 237

  Fly   258 FWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNR 322
            .|||||.|.....|.|:||:.:||..|  :.|..:.|||.|||..|....|.||..:|:...:..
Yeast   238 LWRKNRQRTHVPQCLGIDIDHSFGFQW--EKAHTHACSEEYSGETPFEAWEASAWYKYINETKGD 300

  Fly   323 VKL--SLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTS----ASI 381
            .|:  .:|:||:.:.|.|||.|:.:.:|..:..|..::...:..|....|..|...::    .|.
Yeast   301 YKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSD 365

  Fly   382 LYE--ASGSLDDFAY---------------GNLGIPLSYTLELPGDEFHVPAHDIIHVCKETFAG 429
            ::.  .:||..||.|               ||.|             |.:|..:|..|.|||:|.
Yeast   366 IFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHG-------------FLLPPENIKPVGKETYAA 417

  Fly   430 ---FIEFI 434
               |.:|:
Yeast   418 LKYFCDFL 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_648116.2	Peptidase_M14	152..429	CDD:459730	94/307 (31%)
ECM14	NP_012000.1	M14_CP_A-B_like	121..425	CDD:349433	97/321 (30%)