DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8563 and cpa4

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001002217.1	Gene:	cpa4 / 431764	ZFINID:	ZDB-GENE-040704-61	Length:	417	Species:	Danio rerio

Alignment Length:	412	Identity:	124/412 - (30%)
Similarity:	197/412 - (47%)	Gaps:	41/412 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 HGDENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGVSYEMQPLMELMAAL 102
            |.:.....:::.....|:.||||  |..     .|..|........:||   |.::..::
Zfish    29 HAESEDHIHILKELDEDSGLDFW--THG-----FSTERPVDVRVPHASL---YAVKDFLK----- 78

  Fly   103 QANSSFA--DDNYDGEYEECQQDECEQAERPRRRTRRQARGFFSHYPRYHE---VLSFMSGLAAR 162
            :.|..|.  .:|.....:|.:.:....||     |.|.|:.|  .:..||:   :.|||..|.|.
Zfish    79 ENNIPFTVMINNVQDLLDEQKAEMVSNAE-----TERNAKIF--DFAAYHDLDTIYSFMDTLVAS 136

  Fly   163 YPQFCRYESLGRSNEGRHIAALSISLNSRVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNL- 226
            :|......::|.|.|.|.:.||..|.....||  ..:|.|..|.|||:|..:.:::|.::.|:.
Zfish   137 HPNLISKINIGNSYENRPMYALKFSTGGENRP--AIWIDAGIHAREWVTQASAVWIANKMASDYG 199

  Fly   227 --RAFTRVLQDVEIFLVPLVNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGA 289
              .:.|.:|..::::|:.:.|||||.:|||.:|.|||.|....|.||.|.|.|||:...:...||
Zfish   200 VDPSVTSLLGQMDVYLMIVTNPDGYSFTHTDNRMWRKTRSVNPGSSCRGTDPNRNWDAGFGGPGA 264

  Fly   290 SQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTL 354
            |:|.||:.|.|...:||.|...||..::.:.| .|..:.:||:.:.:.|||||....:|.. ..|
Zfish   265 SKNPCSDSYHGPYAHSEVEVKNVVDLIKGHGN-FKSFISIHSYSQLLMYPYGYTCTNIPDQ-SEL 327

  Fly   355 RSVALRAANQIGRYRGTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPGD---EFHVPA 416
            .:|...|..::.....|:|..|:...|:|:|||...|:.| |:||..|:..||...   .|.:||
Zfish   328 HAVGTAAIKELMSLYNTKYQVGSICKIIYQASGGSIDWTY-NIGIKYSFAFELRDTGLYGFLLPA 391

  Fly   417 HDIIHVCKETFAG---FIEFIR 435
            :.||...:||:.|   .:|::|
Zfish   392 NQIIPTAEETWLGLKNIMEYVR 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	102/302 (34%)
cpa4	NP_001002217.1	Propep_M14	27..97	CDD:280416	15/82 (18%)
cpa4	NP_001002217.1	M14_CPA	115..415	CDD:133081	103/306 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820