DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8563 and Cpa5

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	430	Identity:	122/430 - (28%)
Similarity:	199/430 - (46%)	Gaps:	39/430 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LGIANNLAGYEGYTKYTVQHGDENAFKYMVDLQTNDAE-LDFWLLTRNSSV---LTVSPRRKTQF 79
            |.:|.....:.|.....|...:|.....:.||:....: :|||......|:   :.|........
  Rat    28 LAVAWGQVNFTGDQVLRVLAKNEKQLSLLRDLEIQKPQKVDFWRGPARPSLPVDMRVPFSELPSV 92

  Fly    80 EASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPRRRTRRQARGF-F 143
            :|.|.|.|::|.:. :.::...|                    ||...|....||..|...|| :
  Rat    93 KAYLKSHGLAYSVM-IKDIQVLL--------------------DEERDAMARSRRLERSTNGFSY 136

  Fly   144 SHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRPRRVA-YIQAATHGR 207
            |.|....|:.:::....|.:........:|:|.|.|.|..|..|...   |.|.| :|....|.|
  Rat   137 SSYHTLEEIYNWIDNFVAEHSNLVSKIHIGKSFENRSILVLKFSTGG---PNRTAIWIDTGIHSR 198

  Fly   208 EWITTQTVLYLAYELL---SNLRAFTRVLQDVEIFLVPLVNPDGYEYTHTTDRFWRKNRHRYAGH 269
            ||||..|.::::.:::   |......:||..::||:..:.||||:.:||:.:|.||||:....|.
  Rat   199 EWITHATGIWISQKIVNAYSKDHVLKKVLNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSIQPGI 263

  Fly   270 SCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRVKLSLDVHSFGK 334
            .|.|||:|||:...:...|:::|.|||.|.|.||.||||.:|:|.::..:.| .|..:.:||:.:
  Rat   264 VCVGVDLNRNWRTGFGGNGSNKNPCSETYRGPAPESEPEVAAIVAFITGHGN-FKAMISIHSYSQ 327

  Fly   335 FIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYEASGSLDDFAYGNLGI 399
            .:.||||::...| |....|..:|..|...:.:..|..|..|:.::.||.|||...|:||.: ||
  Rat   328 MVMYPYGHSLEPV-PNHKELFELAKDAVKALYKVHGMEYIFGSISTTLYSASGITVDWAYDS-GI 390

  Fly   400 PLSYTLELPGD---EFHVPAHDIIHVCKETFAGFIEFIRH 436
            ..:::.||...   .|.:||..|:...:||:......::|
  Rat   391 KYAFSFELRDTGQYGFLLPASQIVPTAEETWMALRTIMKH 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	95/298 (32%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	15/89 (17%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	97/303 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750