Protein Alignment CG8563 and AGTPBP1

DIOPT Version :10

• Sequence 1: NP_648116.2
• Gene: CG8563 / 38826
• FlyBaseID: FBgn0035777
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_001273644.1
• Gene: AGTPBP1 / 23287
• HGNCID: 17258
• Length: 1278
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 101/464 - (21%)
• Similarity: 156/464 - (33%)
• Gaps: 153/464 - (32%)

  Fly    34 YTV-QHGDENAF---------KYMVDLQTNDAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGV 88
            ||: :.||...|         :.::.::.|:.:     |..||.:.:....:...||.|....||
Human   753 YTIPEEGDILKFNSKFESGNLRKVIQIRKNEYD-----LILNSDINSNHYHQWFYFEVSGMRPGV 812

  Fly    89 SYE----------------MQPLM-ELMAALQA-------------------NSSFADDNYDGE- 116
            :|.                ||||| .:..||.|                   .||.|.....|:
Human   813 AYRFNIINCEKSNSQFNYGMQPLMYSVQEALNARPWWIRMGTDICYYKNHFSRSSVAAGGQKGKS 877

  Fly   117 YEEC--------QQDECEQAERPRRRTRRQARGFFSHYPRYHEVLSF-MSGL-AARYPQ--FCRY 169
            |...        :.|.|.               |..|||..:..|.. :..| :|..||  :.|.
Human   878 YYTITFTVNFPHKDDVCY---------------FAYHYPYTYSTLQMHLQKLESAHNPQQIYFRK 927

  Fly   170 ESLGRSNEGRHIAALSISLN---------SRVRPRRVAYIQAATHGRE----WITTQTVLYLAYE 221
            :.|..:..|.....::|:..         ...|.|...::.|..|..|    |:...|:.|
Human   928 DVLCETLSGNSCPLVTITAMPESNYYEHICHFRNRPYVFLSARVHPGETNASWVMKGTLEY---- 988

  Fly   222 LLSNLRAFTRVLQDVEIF-LVPLVNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWN 285
            |:|| ....:.|::..|| :||::||||.          ....||.   |.||.|:||      .
Human   989 LMSN-NPTAQSLRESYIFKIVPMLNPDGV----------INGNHRC---SLSGEDLNR------Q 1033

  Fly   286 YQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRVKLSLDV--HSFGKFIFYPYGYA-KNTV 347
            :|..|.:|...:|         ....:::||...:....:..|.  ||..|.:|. ||.: |.||
Human  1034 WQSPSPDLHPTIY---------HAKGLLQYLAAVKRLPLVYCDYHGHSRKKNVFM-YGCSIKETV 1088

  Fly   348 PPTVGTLRSVALRAANQIGRYRGTRYTT-------------GTSASILYEAS--GSLDDFAYGNL 397
            ..|.....|..:        ...|.|.|             .:|.|.:.|.|  .:.....:..:
Human  1089 WHTNDNATSCDV--------VEDTGYRTLPKILSHIAPAFCMSSCSFVVEKSKESTARVVVWREI 1145

  Fly   398 GIPLSYTLE 406
            |:..|||:|
Human  1146 GVQRSYTME 1154

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_648116.2	Peptidase_M14	152..429	CDD:459730	67/291 (23%)
AGTPBP1	NP_001273644.1	Pepdidase_M14_N	764..898	CDD:407865	27/153 (18%)
		M14_Nna1	921..1191	CDD:349477	63/276 (23%)