DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8563 and Agbl5

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_036020907.1	Gene:	Agbl5 / 231093	MGIID:	2441745	Length:	1007	Species:	Mus musculus

Alignment Length:	409	Identity:	80/409 - (19%)
Similarity:	127/409 - (31%)	Gaps:	178/409 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 RQARGFFSH-YP-RYHEVLSFMSGLAARYPQ------------FCRYESLGRSNEGRHIAALSIS 187
            |.|..||:. || .|.:....:|.|..|:.:            :...|.|..|.:|..:..|:|:
Mouse   268 RGATTFFAFCYPFSYSDCQDLLSQLDQRFSENYSTHSSPLDSIYYHRELLCYSLDGLRVDLLTIT 332

  Fly   188 ----LNSRVRPR-------------------RVAYIQAATHGREWITTQTVL---YLAYELL-SN 225
                |.....||                   |:.::.:..|..|  |..:.:   :|.:.|. .:
Mouse   333 SCHGLRDDREPRLEQLFPDLGTPRPFRFTGKRIFFLSSRVHPGE--TPSSFVFNGFLDFILRPDD 395

  Fly   226 LRAFTRVLQDVEIF-LVPLVNPDGYEYTH-TTDRFWRKNRHRYAGHSCSGVDINRNFGN-----H 283
            .||.|  |:.:.:| |:|::||||....| .||              ..||::||.:..     |
Mouse   396 PRAQT--LRRLFVFKLIPMLNPDGVVRGHYRTD--------------SRGVNLNRQYLKPDAVLH 444

  Fly   284 WNYQGA--------------------------------------SQNLCSEVYSGTAPNSE---- 306
            ....||                                      :.||.:|.:.|.:|:.|
Mouse   445 PAIYGAKAVLLYHHVHSRLNAKSPTNQQPTLHLPPEAPLSDLEKANNLHNEAHLGQSPDGENPAT 509

  Fly   307 -PET--------------------------------SAVVRYLEFNRNRVKLSLDVHSFGKFIFY 338
             |||                                |.|..|::.:.:..|.       |.|:
Mouse   510 WPETEPAEEKTDPVWLMPQPIPELEEPAPDTIPPKESGVAYYVDLHGHASKR-------GCFM-- 565

  Fly   339 PYG--------YAKNTVPPTVGTLRSV-------ALRAANQIGR-YRGTRYTTGTSASILYEASG 387
             ||        ..:|.:.|.:.:|.|.       .....|...| .|..:...|:....:|:|||
Mouse   566 -YGNSFSDESTQVENMLYPKLISLNSAHFDFQGCNFSEKNMYARDRRDGQSKEGSGRVAIYKASG 629

  Fly   388 SLDDFAYGNLGIPLSYTLE 406
            .:.           |||||
Mouse   630 IIH-----------SYTLE 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	76/399 (19%)
Agbl5	XP_036020907.1	Pepdidase_M14_N	102..>214	CDD:407865
Agbl5	XP_036020907.1	M14_AGBL5_like	304..695	CDD:349455	70/373 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900