DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8563 and cpo.2

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_002937157.1	Gene:	cpo.2 / 100487462	XenbaseID:	XB-GENE-22169695	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	443	Identity:	125/443 - (28%)
Similarity:	201/443 - (45%)	Gaps:	68/443 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 YEGYTKYTVQHGDENAFKYMVD-------LQT--NDAELDFW------LLTRNSSVLTVSP-RRK 76
            ||| :..|||:..:|.||...:       |||  |:..||.|      .:...|.:....| ...
Frog    16 YEG-SCLTVQYNGDNVFKITPETSEHAQYLQTLANEWLLDLWRPQTVEQIHEGSDIHVQIPFAYM 79

  Fly    77 TQFEASLSSLGVSYEMQPLMELMAALQANSSFAD-------DNYDGEYEECQQDECEQAERPRRR 134
            .|.:..|....:.||:. :.::...:.:|:..|.       :|||
Frog    80 EQMKQKLLQHSIPYEVL-INDVQKLIDSNTVSAPKIQKASLENYD-------------------- 123

  Fly   135 TRRQARGFFSHYPRYH---EVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRPRR 196
                       |.:||   |:.::|..:..::.:......:|.:.|.|.:..|.|...|. :.::
Frog   124 -----------YTKYHPMDEIYNWMDLMKEKHSEIVSQHYIGCTYELRPMYYLKIGWPSD-KQKK 176

  Fly   197 VAYIQAATHGREWITTQTVLYLAYELLSNLRA---FTRVLQDVEIFLVPLVNPDGYEYTHTTDRF 258
            :.:|....|.||||:.....:...|::|:.:.   ...||:.|:.:::|::|.|||.||.||:|.
Frog   177 IFFIDCGFHAREWISVAFCQWFVNEIVSHYKTDAILANVLKQVDFYVLPVMNIDGYVYTWTTNRL 241

  Fly   259 WRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRV 323
            |||||..:...:|.|||:||||.:.|...|||::..|..:.|....|||||.|:...:|..::.:
Frog   242 WRKNRSPHENGTCYGVDLNRNFDSQWCSIGASRDCNSNTFCGPEAASEPETKALSGLIEKTKSDI 306

  Fly   324 KLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYEASGS 388
            ...|.:||:|:.|..||||.|:. .|....:..||..|..::.......|...:||.|||..|||
Frog   307 LCYLTIHSYGQMILLPYGYKKDP-SPNHDEMMLVAKNAVAKMKEKHNNEYEYESSAVILYYDSGS 370

  Fly   389 LDDFAYGNLGIPLSYTLELPGD---EFHVPAHDIIHVCKETFAGFIEFIRHVS 438
            ..|:.. .|||.|||||||..:   .|.:|...|...|:||....:..:.:::
Frog   371 SGDWTV-ELGIQLSYTLELRDNGTYGFVLPPDQIKPTCEETTTAVMSMVEYIN 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	98/299 (33%)
cpo.2	XP_002937157.1	Propep_M14	36..105	CDD:366995	13/69 (19%)
cpo.2	XP_002937157.1	M14_CPO	124..421	CDD:349466	98/299 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920