DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8563 and cpo.1

DIOPT Version :9

Sequence 1:	NP_001261515.1	Gene:	CG8563 / 38826	FlyBaseID:	FBgn0035777	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_031748368.1	Gene:	cpo.1 / 100145253	XenbaseID:	XB-GENE-989447	Length:	451	Species:	Xenopus tropicalis

Alignment Length:	461	Identity:	130/461 - (28%)
Similarity:	210/461 - (45%)	Gaps:	77/461 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LALCLVGLAGLGIANNLAGYEGYTKYTVQHGDENAFKYMVDLQTND-----------AELDFWLL 62
            |.:|:     |||...:..|     ..||:..:...|  :.|:|.|           .:||.|
Frog     6 LCICI-----LGILTQVGAY-----LKVQYNGDQVLK--LTLKTTDDCEHMQNICKQLQLDLW-- 56

  Fly    63 TRNSSVLTVSPRRK----------TQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEY 117
             :.|.:..:.|.::          .:|:.:|....:.:|:.        ::......|.:..|:|
Frog    57 -KPSRIEDIQPGKEMHVRIPFPLLQKFKENLHQYSIPFEVM--------IKDVQKLIDSSNVGDY 112

  Fly   118 EECQQDECEQAERPRRRTRRQARGFFSHYPRYH---EVLSFMSGLAARYPQFCRYESLGRSNEGR 179
                           ||.::....|  .|..||   |:..:|..:...|........||.:.|.|
Frog   113 ---------------RRQKKILAEF--DYTTYHPMDEIYQWMDQVKEAYSDLVSMHYLGSTYELR 160

  Fly   180 HIAALSISLNSRVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNLRA---FTRVLQDVEIFLV 241
            .|....|...|. :.:::.::....|.||||......:...|:|...:.   ..:||.:::.::|
Frog   161 PIYYFKIGWPSD-KQKKIIWMDCGIHAREWIAVAYCQWFVKEILETHKTNPLLQKVLHNIDFYIV 224

  Fly   242 PLVNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSE 306
            |::|.||:.|:...:|.|||:|..:...||.|||:||||.:.|...|||.|...|.|.||.|.||
Frog   225 PVLNIDGFVYSWNVNRLWRKSRSPHNNGSCYGVDLNRNFNSKWGSIGASNNCRDETYCGTGPASE 289

  Fly   307 PETSAVVRYLEFNRNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVG--TLRSVALRAANQIGRYR 369
            ||.:||.:.|...::.|...|.:||:|:.:..||||.|:   |::.  .:.:||.:||.::....
Frog   290 PEVNAVSKLLGSLKSDVLCFLTIHSYGQLLLLPYGYTKD---PSINHEEMINVAQKAAAKLQEKH 351

  Fly   370 GTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPGDEFH---VPAHDIIHVCKETFAGFI 431
            ||.|..|:::.:||..|||..|:| .:|||..|||.||.....|   :||:.|...|:||.||.:
Frog   352 GTEYRVGSTSHLLYSNSGSSRDWA-TDLGINFSYTFELRDTGAHGFILPANQIRPTCEETMAGVM 415

  Fly   432 EFIRHV 437
            ..:.||
Frog   416 TIVEHV 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8563	NP_001261515.1	M14_CP_A-B_like	146..437	CDD:199844	102/301 (34%)
cpo.1	XP_031748368.1	Propep_M14	36..105	CDD:396700	10/79 (13%)
cpo.1	XP_031748368.1	M14_CPO	124..421	CDD:349466	102/301 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920