Protein Alignment CG8564 and CPA4

DIOPT Version :10

• Sequence 1: NP_001261514.1
• Gene: CG8564 / 38825
• FlyBaseID: FBgn0035776
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 87/309 - (28%)
• Similarity: 137/309 - (44%)
• Gaps: 47/309 - (15%)

  Fly    80 LGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDIGPNGRFTVPVIHVGEHCRKTVFIEAG 144
            :||:.|.|.:..|:                      |..|...|            |..|::.||
Human   149 IGHSFENRPMYVLK----------------------FSTGKGVR------------RPAVWLNAG 179

  Fly   145 THAREWISVSTALNCIYQLTERYTRN---IEVLRKLRFIIVPLVNPDGYEYSRTKNPKWRKNRRP 206
            .|:|||||.:||:....::...|.|:   ..:|.|:...::|:.|||||.|::|:|..|||.|..
Human   180 IHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSR 244

  Fly   207 HKSAKFVGTDCNRNYDIFWNSGPSKIN--RNTYKGESPFSEPETRAMRCILDRMSSNLLFFLSLH 269
            :..:..:|.|.|||::..:....:..|  ...|.|....||.|.:::...:.: ..|...|:.||
Human   245 NPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK-HGNFKGFIDLH 308

  Fly   270 SYGQSIMYPWGYCRDNPIYWRELSSLANSGKSAIKSYNGREYRTGSISCLTKRTIAGSVVDYVY- 333
            ||.|.:|||:||.........||..:|.....|:.|.:|.||:.|. :|.|....:||.:|:.|
Human   309 SYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGP-TCTTVYPASGSSIDWAYD 372

  Fly   334 -GVLKVPMALVMEL-PSRELGFQPPVEMISQIGHESWYGIREMCKRSFD 380
             |   :..|...|| .:...||..|...|.....|:|.|::.:.:...|
Human   373 NG---IKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	Peptidase_M14	60..370	CDD:459730	85/297 (29%)
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505
		M14_CPA	118..419	CDD:349442	87/309 (28%)