DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8564 and cpa1

DIOPT Version :9

Sequence 1:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001107681.1	Gene:	cpa1 / 497006	XenbaseID:	XB-GENE-960032	Length:	420	Species:	Xenopus tropicalis

Alignment Length:	335	Identity:	85/335 - (25%)
Similarity:	149/335 - (44%)	Gaps:	49/335 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDI 118
            |..:.::|.::..|.....:.|....:|.::|.|.:..|:                      |..
Frog   124 YHTFDEINAFIDNLVSENPNLVSKIQIGSSYEGRPLNVLK----------------------FST 166

  Fly   119 GPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRFI 180
            |||              |...:|:.|.|:|||::.::|:....::...:.::   ...|.::..:
Frog   167 GPN--------------RPAFWIDTGIHSREWVTQASAVWFAKKIVTDFGKDPSLTNTLNQMDIL 217

  Fly   181 IVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFWNSGPSKIN--RNTYKGESPF 243
            |..:.||||:.|:...:..|||.|.|:..:..||||.|||:|..:....|..|  ..||:|.:..
Frog   218 IEIVTNPDGFVYTHKSDRMWRKTRSPNSGSLCVGTDPNRNWDAGFGGPGSSSNPCTETYRGRAAH 282

  Fly   244 SEPETRAMRCILDRMSS--NLLFFLSLHSYGQSIMYPWGYCRDNPIYWRELSSLANSGKSAIKSY 306
            ||||.:|   |:|.:.|  |:..|:|:|||.|.:::|:||.........||::::....:|:.|.
Frog   283 SEPEVKA---IVDFVKSHGNIKGFVSIHSYSQMLLFPYGYTNTRVPDHDELNAVSKKAITALASL 344

  Fly   307 NGREYRTGSISCLTKRTIAGSVVDYVYGVLKVPMALVMEL-PSRELGFQPPVEMISQIGHESWYG 370
            .|..|..||| ..|....:|..:|:.|. ..:..:...|| .:...||..|...|.....|:|..
Frog   345 YGTAYTYGSI-ISTIYQASGGTIDWTYN-QGIKHSYSFELRDTGRYGFALPANQIIPTAEETWLA 407

  Fly   371 IREMCKRSFD 380
            :..:.:.:.|
Frog   408 LTILIEHTRD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	M14_CP_A-B_like	54..377	CDD:199844	84/330 (25%)
cpa1	NP_001107681.1	Propep_M14	27..99	CDD:280416
		MpaA	28..402	CDD:225421	82/318 (26%)
		M14_CPA	119..418	CDD:133081	85/335 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920