DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8564 and cpa2

DIOPT Version :9

Sequence 1:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001003446.2	Gene:	cpa2 / 445052	ZFINID:	ZDB-GENE-040801-182	Length:	422	Species:	Danio rerio

Alignment Length:	334	Identity:	93/334 - (27%)
Similarity:	147/334 - (44%)	Gaps:	57/334 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDI 118
            |.|...:..::..|...:::.:....:|.|:|.|.:..|:                      |..
Zfish   120 YHDLDTIYSFMDTLVASHSNLISKVKIGSTYENRPMYVLK----------------------FST 162

  Fly   119 GPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN----IEVLRKLRF 179
            |            ||: :..::|:||.|||||:|.::|:....::...:..|    ..||.|:..
Zfish   163 G------------GEN-KPAIWIDAGIHAREWVSHASAVWIADRIATDFKENRALARNVLSKMDI 214

  Fly   180 IIVPLVNPDGYEYSR-TKNP---KWRKNRRPHKSAKFVGTDCNRNYDIFWNSGPSKIN---RNTY 237
            .::.:.|||||.:|. |..|   .|||:|....:....|.|.|||:|..: |||...:   ...|
Zfish   215 YLMIVANPDGYVFSHLTVRPFHRLWRKSRSVTSNPNCPGVDLNRNFDAEF-SGPGASDDPCAEDY 278

  Fly   238 KGESPFSEPE-TRAMRCILDRMSSNLLFFLSLHSYGQSIMYPWGYCRDNPIYWRELSSLANSGKS 301
            :|.|..||.| |.....||..  .|...|::||:|.|.:|||:||...|.....:|..:|.....
Zfish   279 RGPSAHSEIEVTNIADFILSH--GNFKSFMTLHAYSQLLMYPYGYTGSNAPDQPDLHDVATQANK 341

  Fly   302 AIKSYNGREYRTGSISCLTKRTIAGSVVDYVY--GVLKVPMALVMEL-PSRELGFQPPVEMISQI 363
            |:.|::|..|:.||| ..|....:|:.||:.|  |   :......|| .:.|.||..|.:.|...
Zfish   342 ALNSWHGTIYKVGSI-FHTIEQASGASVDWAYQHG---IKYCFAFELRDTGEYGFLLPADQIVST 402

  Fly   364 GHESWYGIR 372
            ..|:|:.:|
Zfish   403 ARETWFALR 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	M14_CP_A-B_like	54..377	CDD:199844	93/334 (28%)
cpa2	NP_001003446.2	Propep_M14	27..97	CDD:280416
cpa2	NP_001003446.2	Peptidase_M14_like	115..420	CDD:299699	93/334 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920