DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8564 and cpa5

DIOPT Version :9

Sequence 1:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_954965.1	Gene:	cpa5 / 246092	ZFINID:	ZDB-GENE-020514-1	Length:	419	Species:	Danio rerio

Alignment Length:	331	Identity:	89/331 - (26%)
Similarity:	149/331 - (45%)	Gaps:	57/331 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TYLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFD 117
            ||.|...:|.::..|.....:.|...::|.::|||.:..|:                      |.
Zfish   122 TYHDLNSINSFMDMLVAENRNMVSKVVIGQSYEKRPLNVLK----------------------FS 164

  Fly   118 IGPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRF 179
            .|.|              |..::|:.|.|:|||::.::.:....::.:.|.|:   .::|.....
Zfish   165 TGAN--------------RPGIWIDTGIHSREWVTQASGVWFAKKIVKDYGRDPVLTDILNSHDI 215

  Fly   180 IIVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFWNSGPSKIN--RNTYKGESP 242
            .:..:.||||:.|:.||:..|||.|:|:..:..||.|.|||:|..:..|.|..|  ..||:|.|.
Zfish   216 FLEIVTNPDGFVYTHTKDRMWRKTRKPNPGSSCVGVDPNRNWDAGFGGGGSSNNPCTETYRGPSA 280

  Fly   243 FSEPETRAMRCILDRMSSN--LLFFLSLHSYGQSIMYPWGY----CRDNPIYWRELSSLANSGKS 301
            .||||.:|   |:|.:.|:  :..|:|:|||.|.::||:||    .:|.    .||..:|....:
Zfish   281 HSEPEVKA---IVDFVKSHGKIKAFVSIHSYSQMLLYPYGYTYTAAKDK----AELHEVARKAIT 338

  Fly   302 AIKSYNGREYRTGSISCLTKRTIAGSVVDYVYGVLKVPMALVMEL-PSRELGFQPPVEMISQIGH 365
            :::|.....|..||| ..|....:|..:|:.|. ..:..:...|| .:...||..|...|.....
Zfish   339 SLQSLYNTRYTYGSI-ITTIYQASGGTIDWTYN-QGIKYSYTFELRDTGRYGFILPANQIVPTAE 401

  Fly   366 ESWYGI 371
            |:|..:
Zfish   402 ETWLAL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	M14_CP_A-B_like	54..377	CDD:199844	88/330 (27%)
cpa5	NP_954965.1	Propep_M14	27..100	CDD:280416
cpa5	NP_954965.1	Peptidase_M14_like	118..417	CDD:299699	89/331 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920