Protein Alignment CG8564 and CPB1

DIOPT Version :10

• Sequence 1: NP_001261514.1
• Gene: CG8564 / 38825
• FlyBaseID: FBgn0035776
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001862.2
• Gene: CPB1 / 1360
• HGNCID: 2299
• Length: 417
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 117/415 - (28%)
• Similarity: 186/415 - (44%)
• Gaps: 77/415 - (18%)

  Fly    15 VVERLHLNIKCQTAK----DRSRTDATTALRRLVIPRPDILHTYLDYK-------------QVNQ 62
            |.:..|:||..:.|.    |..:.|:.|.::.         |:.:|::             :.|:
Human    32 VEDENHINIIRELASTTQIDFWKPDSVTQIKP---------HSTVDFRVKAEDTVTVENVLKQNE 87

  Fly    63 YLQY--LAQRYAHFV------HVHILGHTHEKREIRALEINWMNSENVEL-SPQMREHSPRLFD- 117
             |||  |.....:.|      .|...||::||..      .|   |.:|. :.|:...:|.|..
Human    88 -LQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN------KW---ETIEAWTQQVATENPALISR 142

  Fly   118 --IGP--NGRFTVPVIHVGE--HCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRNI---EV 173
              ||.  .|| .:.::.||:  ..:..:|::.|.|||||||.:.....:.:....|.|.|   |:
Human   143 SVIGTTFEGR-AIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTEL 206

  Fly   174 LRKLRFIIVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFW-NSGPSKINRN-- 235
            |.||.|.::|::|.|||.|:.||:..|||.|..|..:..:|||.|||:|..| ..|.|   ||
Human   207 LDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGAS---RNPC 268

  Fly   236 --TYKGESPFSEPETRAMRCILDRMSSNLLFFLSLHSYGQSIMYPWGYC----RDNPIYWRELSS 294
              ||.|.:..||.||:|:...:....|::..:|::|||.|.::||:.|.    .:|    .||::
Human   269 DETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENN----AELNA 329

  Fly   295 LANSGKSAIKSYNGREYRTGSISCLTKRTIAGSVVDYVYGVLKVPMALVMEL-PSRELGFQPPVE 358
            ||.:....:.|.:|.:|..|. ...|....||...|:.|. ..:..:...|| .:...||..|..
Human   330 LAKATVKELASLHGTKYTYGP-GATTIYPAAGGSDDWAYD-QGIRYSFTFELRDTGRYGFLLPES 392

  Fly   359 MISQIGHESWYGIREMCKRSFDLRH 383
            .|.....|::..|:.:.  |:.|.|
Human   393 QIRATCEETFLAIKYVA--SYVLEH 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	Peptidase_M14	60..370	CDD:459730	103/338 (30%)
CPB1	NP_001862.2	Propep_M14	28..104	CDD:460505	16/81 (20%)
		M14_CPB	114..413	CDD:349443	97/319 (30%)