Protein Alignment CG8564 and CPA2

DIOPT Version :10

• Sequence 1: NP_001261514.1
• Gene: CG8564 / 38825
• FlyBaseID: FBgn0035776
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001860.2
• Gene: CPA2 / 1358
• HGNCID: 2297
• Length: 419
• Species: Homo sapiens
• Alignment Length: 336
• Identity: 90/336 - (26%)
• Similarity: 154/336 - (45%)
• Gaps: 51/336 - (15%)

  Fly    54 YLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDI 118
            |...::::|.:..|...:...|....:|.:.|.|.:..|:                      |..
Human   123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLK----------------------FST 165

  Fly   119 GPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRFI 180
            |.:              :..::::||.|||||::.:|||....::...|.::   ..:|..|...
Human   166 GGD--------------KPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIF 216

  Fly   181 IVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFWNSGPSKINR---NTYKGESP 242
            ::|:.|||||.:|:|||..|||.|.....:..||.|.|||:|..: .||...:.   ::|.|.|.
Human   217 LLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGF-GGPGASSNPCSDSYHGPSA 280

  Fly   243 FSEPETRAMRCILDRMSSN--LLFFLSLHSYGQSIMYPWGYCRDNPIYWRELSSLANSGKSAIKS 305
            .||.|.::   |:|.:.|:  :..|::||||.|.:|:|:||.......:.|||.:|.....:::|
Human   281 NSEVEVKS---IVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRS 342

  Fly   306 YNGREYRTGSISCLTKRTIAGSV-VDYVYGVLKVPMALVMELPSRELGFQPPVEMISQIGHESWY 369
            .:|.:|:.|.|..:..:...||: ..|.||: |...|..:....| .||..|...|.....|:|.
Human   343 LHGTKYKVGPICSVIYQASGGSIDWSYDYGI-KYSFAFELRDTGR-YGFLLPARQILPTAEETWL 405

  Fly   370 GIREMCKRSFD 380
            |::.:.:...|
Human   406 GLKAIMEHVRD 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	Peptidase_M14	60..370	CDD:459730	87/318 (27%)
CPA2	NP_001860.2	Propep_M14	28..102	CDD:460505
		M14_CPA	118..417	CDD:349442	90/336 (27%)