DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8564 and cpo.2

DIOPT Version :9

Sequence 1:	NP_001261514.1	Gene:	CG8564 / 38825	FlyBaseID:	FBgn0035776	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_002937157.1	Gene:	cpo.2 / 100487462	XenbaseID:	XB-GENE-22169695	Length:	454	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	100/368 - (27%)
Similarity:	168/368 - (45%)	Gaps:	67/368 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 YLDYKQVNQYLQYLAQRYAHFVHVHILGHTHEKREIRALEINWMNSENVELSPQMREHSPRLFDI 118
            |....::..::..:.::::..|..|.:|.|:|.|.:..|:|.|.:.:.
Frog   127 YHPMDEIYNWMDLMKEKHSEIVSQHYIGCTYELRPMYYLKIGWPSDKQ----------------- 174

  Fly   119 GPNGRFTVPVIHVGEHCRKTVFIEAGTHAREWISVSTALNCIYQLTERYTRN---IEVLRKLRFI 180
                             :|..||:.|.||||||||:.....:.::...|..:   ..||:::.|.
Frog   175 -----------------KKIFFIDCGFHAREWISVAFCQWFVNEIVSHYKTDAILANVLKQVDFY 222

  Fly   181 IVPLVNPDGYEYSRTKNPKWRKNRRPHKSAKFVGTDCNRNYDIFWNS-GPSK-INRNTYKGESPF 243
            ::|::|.|||.|:.|.|..|||||.||::....|.|.|||:|..|.| |.|: .|.||:.|....
Frog   223 VLPVMNIDGYVYTWTTNRLWRKNRSPHENGTCYGVDLNRNFDSQWCSIGASRDCNSNTFCGPEAA 287

  Fly   244 SEPETRAMRCILDRMSSNLLFFLSLHSYGQSIMYPWGYCRDNPIYWRELSSLANSGKSAIKSYNG 308
            |||||:|:..::::..|::|.:|::|||||.|:.|:||.:|......|:..:|.:..:.:|..:.
Frog   288 SEPETKALSGLIEKTKSDILCYLTIHSYGQMILLPYGYKKDPSPNHDEMMLVAKNAVAKMKEKHN 352

  Fly   309 REYRTGSISCLTKRTIAGSVVDYVYGVLKVPMALVMEL-PSRELGFQPPVEMISQIGHESWYGIR 372
            .||...| |.:.....:||..|:.. .|.:.::..:|| .:...||..|.:.|.....|:...:.
Frog   353 NEYEYES-SAVILYYDSGSSGDWTV-ELGIQLSYTLELRDNGTYGFVLPPDQIKPTCEETTTAVM 415

  Fly   373 EMCKRSFDLRHQIVREKEPPLPWPSRHESSNEGVAIENTSTTT 415
            .|.                        |..||.. :||:..||
Frog   416 SMV------------------------EYINEEY-LENSGVTT 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8564	NP_001261514.1	M14_CP_A-B_like	54..377	CDD:199844	93/328 (28%)
cpo.2	XP_002937157.1	Propep_M14	36..105	CDD:366995
cpo.2	XP_002937157.1	M14_CPO	124..421	CDD:349466	94/353 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020