Protein Alignment smid and CDC48

DIOPT Version :9

• Sequence 1: NP_523959.2
• Gene: smid / 38824
• FlyBaseID: FBgn0016983
• Length: 944
• Species: Drosophila melanogaster
• Sequence 2: NP_010157.1
• Gene: CDC48 / 851431
• SGDID: S000002284
• Length: 835
• Species: Saccharomyces cerevisiae
• Alignment Length: 718
• Identity: 237/718 - (33%)
• Similarity: 357/718 - (49%)
• Gaps: 172/718 - (23%)

  Fly   250 FRDIGGMDSTLKELCEML-IHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFLARAISGQLKMPLM 313
            :.||||....:.::.||: :.::.|:.:..:|:.|.||:|::||||.|||.:|||::.:......
Yeast   213 YDDIGGCRKQMAQIREMVELPLRHPQLFKAIGIKPPRGVLMYGPPGTGKTLMARAVANETGAFFF 277

  Fly   314 EIPATELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIVSQLISSL 378
            .|...|::..::||||..:|:.|::|...:|.::||||||:|...|...:.::|||:||||::.:
Yeast   278 LINGPEVMSKMAGESESNLRKAFEEAEKNAPAIIFIDEIDSIAPKRDKTNGEVERRVVSQLLTLM 342

  Fly   379 DNLKANEFGQSVVVIAATTRPDVLDPGLRRIGRFDHEIAIHIPSRKERREILRIQCEGLSVDPKL 443
            |.:||.   .:|||||||.||:.:||.|||.||||.|:.|.||....|.|:|||..:.:.:...:
Yeast   343 DGMKAR---SNVVVIAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEVLRIHTKNMKLADDV 404

  Fly   444 NYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEPSEDAGET 508
            :.:.:|..|.||||||:.:|.|.||        |::.||       .|..:.||:||.     :.
Yeast   405 DLEALAAETHGYVGADIASLCSEAA--------MQQIRE-------KMDLIDLDEDEI-----DA 449

  Fly   509 PVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKTPKKSAEK 573
            .|.||.|
Yeast   450 EVLDSLG---------------------------------------------------------- 456

  Fly   574 PTDAAMDVDNVAPEEPKKAVEQEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNFCLTLIDFV 638
                                                                      :|:.:|.
Yeast   457 ----------------------------------------------------------VTMDNFR 463

  Fly   639 DAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTAPSGVLLCG 703
            .|:....|||.||..:...:.||||:|.|::|:||||..|..||.:|:...:.||:...|||..|
Yeast   464 FALGNSNPSALRETVVESVNVTWDDVGGLDEIKEELKETVEYPVLHPDQYTKFGLSPSKGVLFYG 528

  Fly   704 PPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVIFFDEFDSLC 768
            |||.||||||||:|.|...||||||||||::|:.||||..:|..|.:||.:||.|:|.||.||:.
Yeast   529 PPGTGKTLLAKAVATEVSANFISVKGPELLSMWYGESESNIRDIFDKARAAAPTVVFLDELDSIA 593

  Fly   769 PKRSDG-GDGNNSGTRIVNQLLTEMDGVEERKGVYILAATNRPDIIDPAILRPGRLDTILYVGFP 832
            ..|... ||...:..|:||||||||||:..:|.|:::.||||||.||||||||||||.::||..|
Yeast   594 KARGGSLGDAGGASDRVVNQLLTEMDGMNAKKNVFVIGATNRPDQIDPAILRPGRLDQLIYVPLP 658

  Fly   833 EQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLRQSL------- 890
            :::.|..||.|..:  |.| |...::|..||..|:|::||||..:|::|:.::::.|:
Yeast   659 DENARLSILNAQLR--KTP-LEPGLELTAIAKATQGFSGADLLYIVQRAAKYAIKDSIEAHRQHE 720

  Fly   891 -------NNGDTNLDD--------------LCVRSQHFQEALQQLRPSVNEQDRKIYDKLRLKYA 934
                   ...|..:.|              ..:..:||.||::..:.||::.:.:.|:....:..
Yeast   721 AEKEVKVEGEDVEMTDEGAKAEQEPEVDPVPYITKEHFAEAMKTAKRSVSDAELRRYEAYSQQMK 785

  Fly   935 APR 937
            |.|
Yeast   786 ASR 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330
		SpoVK	271..919	CDD:223540	227/676 (34%)
		AAA	287..418	CDD:278434	58/130 (45%)
		P-loop_NTPase	679..>716	CDD:304359	19/36 (53%)
		AAA	699..830	CDD:278434	78/131 (60%)
CDC48	NP_010157.1	CDC48	48..785	CDD:273521	235/713 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810