DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment smid and AT1G62130

DIOPT Version :9

Sequence 1:	NP_523959.2	Gene:	smid / 38824	FlyBaseID:	FBgn0016983	Length:	944	Species:	Drosophila melanogaster
Sequence 2:	NP_176404.3	Gene:	AT1G62130 / 842509	AraportID:	AT1G62130	Length:	1043	Species:	Arabidopsis thaliana

Alignment Length:	961	Identity:	203/961 - (21%)
Similarity:	342/961 - (35%)	Gaps:	325/961 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YLEEHIGETYLDVKQMTRELMQ-KYPEYSR---------RKFGPFRQLVHQAF--SIISESYNLD 72
            ||.||.....|.|..|....|. .|..|:.         ...||....::|..  ..::.|:|
plant   320 YLSEHTKYVLLAVSDMHLNKMNIGYAPYASDLTILNPRILLSGPAGSEIYQEILAKALANSFN-- 382

  Fly    73 KVSSSEEDCVSEDSEP---PPTNSVMNNMMNSLYSQPRKPLAPKPI--SEPIDISSGDENEDDSN 132
                  ...:..||.|   ..|.....::||          .|..|  .:.:|:|||
plant   383 ------AKLLIFDSNPILGVMTAKEFESLMN----------GPALIDRGKSLDLSSG-------- 423

  Fly   133 TKTTNGDGVAAAAAPPPPT-PAVQGSALKRLMEEVPEIAVAAKKVAKPNTIHVSSSEAIQKLHQV 196
                .||    ::.|.|.| |...|:.:..|:                 .:|...:        :
plant   424 ----QGD----SSIPSPATSPRSFGTPISGLL-----------------ILHWGKT--------L 455

  Fly   197 VGNRAKNLSEDAVPRSKDHRNVP-GLYQQL----HQNQSRDRLRKFKRDLEVQHPTESFRDIGGM 256
            .|:|.:...::..|.....|..| |...::    .:|.|.      |..:..::|.....|:|
plant   456 AGDRVRFFGDELCPGLPTSRGPPYGFIGKVLLVFDENPSA------KVGVRFENPVPDGVDLG-- 512

  Fly   257 DSTLKELCEMLIHIKSPEFYFQLGLLPSRGLLLHGPPGCGKTFLARAISGQLKM----PLMEIPA 317
                 :||||                             |..|...|...|.:.    .|.|:..
plant   513 -----QLCEM-----------------------------GHGFFCSATDLQFESSASDDLNELLV 543

  Fly   318 TELIGGISGESEERIREVFDQAIGYSPCVLFIDEIDAIGGNRQWASKDMERRIV--SQLISSLDN 380
            |:|.            ||........|.::|:              ||.|:..|  |...|:..:
plant   544 TKLF------------EVAHDQSRTCPVIIFL--------------KDAEKYFVGNSHFCSAFKS 582

  Fly   381 LKANEFGQSVVVIAATTRPDVLDPGLRRIGR----FDHEIAIHIPSRKERREILR-----IQCEG 436
             |......:::||.:.|..|  :|..:.|||    |.:::.|::|   :..|:|:     :..:.
plant   583 -KLEVISDNLIVICSQTHSD--NPKEKGIGRLTDLFVNKVTIYMP---QGEELLKSWKYHLDRDA 641

  Fly   437 LSVDPKLNYDKIAELTPGYVGADLMALVSRAASVAVKRRSMKKFRELHAASEKNMTTVTLDDDEP 501
            .::..|.||:.: .:..|..|.:.                            :.:.|:.:.|...
plant   642 ETLKMKANYNHL-RMVLGRCGIEC----------------------------EGIETLCMKDLTL 677

  Fly   502 SEDAGETPVPDSKGEETAKDAEAEQKVDGDKETSAKDKSEGDSPNIETPKKATNGNSSIKSPQKT 566
            ..|:.|                   |:.|...:.....:.|..|::..
plant   678 RRDSAE-------------------KIIGWALSHHIKSNPGADPDVRV----------------- 706

  Fly   567 PKKSAEKPTDAAMDVDNVAPEEPKKAVE-QEVDSSSSNDEYYEPTLAELTNFLDNPPEEFADPNF 630
                            .::.|..|..:| .|::|..|..:.......|:::.:  ||.|..
plant   707 ----------------ILSLESLKCGIELLEIESKKSLKDIVTENTFEISDII--PPSEIG---- 749

  Fly   631 CLTLIDFVDAIKVMQPSAKREGFITVPDTTWDDIGALEKIREELKLAVLAPVKYPEMLERLGLTA 695
                                        .|:|||||||.:::.||..|:.|.::||:..:..||.
plant   750 ----------------------------VTFDDIGALENVKDTLKELVMLPFQWPELFCKGQLTK 786

  Fly   696 P-SGVLLCGPPGCGKTLLAKAIANEAGINFISVKGPELMNMYVGESERAVRACFQRARNSAPCVI 759
            | :|:||.||.|.|||:||||:|.|||.|.|::.    |:.:..|.|:.|:|.|..|...:|.:|
plant   787 PCNGILLFGPSGTGKTMLAKAVATEAGANLINMS----MSRWFSEGEKYVKAVFSLASKISPSII 847

  Fly   760 FFDEFDSLCPKRSDGGDGNNSGTRIVNQLLTEMDGV--EERKGVYILAATNRPDIIDPAILRPGR 822
            |.||.:|:.         :....:..|:.:...||:  .|::.|.:|||||||..:|.|::|  |
plant   848 FLDEVESML---------HRYRLKTKNEFIINWDGLRTNEKERVLVLAATNRPFDLDEAVIR--R 901

  Fly   823 LDTILYVGFPEQSERTEILKATTKNGKRPVLADDVDLDEIAAQTEGYTGADLAGLVKQASMFSLR 887
            |...|.||.|:...|::|||...   .:..|:.|.|:||:|:.|.||:|.||..|...|:...:.
plant   902 LPHRLMVGLPDARSRSKILKVIL---SKEDLSPDFDIDEVASMTNGYSGNDLKNLCVTAARRRII 963

  Fly   888 QSLNNGDTNLD----------------DLCV-RSQHFQEALQQLRPSVNEQ 921
            :.:....:..|                ||.| :.:.|:.||:.:..|::.:
plant   964 EIVEKEKSERDAAVAEGRVPPAGSGGSDLRVLKMEDFRNALELVSMSISSK 1014

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
smid	NP_523959.2	Nucleolin_bd	2..71	CDD:293330	14/62 (23%)
		SpoVK	271..919	CDD:223540	151/683 (22%)
		AAA	287..418	CDD:278434	28/140 (20%)
		P-loop_NTPase	679..>716	CDD:304359	18/37 (49%)
		AAA	699..830	CDD:278434	49/132 (37%)
AT1G62130	NP_176404.3	P-loop_NTPase	749..>816	CDD:304359	34/98 (35%)
		AAA	789..912	CDD:214640	52/137 (38%)
		AAA	791..910	CDD:278434	50/133 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810